Stereoselective functionalization of the 1'-position of 4'-thionucleosides.

Stereoselective functionalization of the 1'-position of 4'-thionucleosides.

Organic letters (2006-09-08)

Prashantha Gunaga, Hea Ok Kim, Hyuk Woo Lee, Dilip K Tosh, Jae-Sang Ryu, Sun Choi, Lak Shin Jeong

RÉSUMÉ

Stereoselective synthesis of novel 1'-alpha-substituted-4'-thionucleosides was achieved starting from D-gulonic acid gamma-lactone via stereoselective nucleophilic substitution.

MATÉRIAUX

Référence du produit

Marque

Description du produit

310301

Sigma-Aldrich

L-Gulonic acid γ-lactone, 95%