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1612608

USP

Silver sulfadiazine

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

Silver(I) sulfadiazine, Sulfadiazine silver

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About This Item

Formule empirique (notation de Hill):
C10H9AgN4O2S
Numéro CAS:
Poids moléculaire :
357.14
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

sulfadiazine

Fabricant/nom de marque

USP

Pf

285 °C (dec.) (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

Nc1ccc(cc1)S(=O)(=O)N([Ag])c2ncccn2

InChI

1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1

Clé InChI

UEJSSZHHYBHCEL-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Silver sulfadiazine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Silver Sulfadiazine Cream

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Frederick W Fuller
Journal of burn care & research : official publication of the American Burn Association, 30(3), 464-470 (2009-04-08)
Silver sulfadiazine cream has an enviable safety record in burn treatment. However, it side effects, exemplified by allergic reactions to its sulfadiazine moiety, silver staining of the treated burn wound, hyperosmolality, methemoglobinemia, and hemolysis due to a congential lack of
Use of silver sulfadiazine in Stevens-Johnson syndrome.
M L Frenia et al.
The Annals of pharmacotherapy, 28(6), 736-737 (1994-06-01)
M Prosdocimi et al.
Minerva medica, 103(6), 533-539 (2012-12-12)
Diabetes-related chronic cutaneous lesions are a serious and common problem, as well as a major cause for hospital admissions, although no general consensus has been reached on the best available treatment for this frequent pathological condition. The primary objective of
Myth: silver sulfadiazine is the best treatment for minor burns.
J Y Chung et al.
The Western journal of medicine, 175(3), 205-206 (2001-08-31)
Andrew C Miller et al.
Journal of the American Academy of Dermatology, 66(5), e159-e165 (2010-08-21)
For decades silver-containing antibiotics such as silver sulfadiazine (SSD) have been applied as standard topical therapy for patients with partial-thickness burns and venous stasis ulcers. This evidence-based review intends to answer the following research question: in ambulatory patients with partial-thickness

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