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1570009

USP

Promethazine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride

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About This Item

Formule empirique (notation de Hill):
C17H20N2S · HCl
Numéro CAS:
58-33-3
Poids moléculaire :
320.88
Numéro Beilstein :
4166397
Numéro MDL:
MFCD00012652
Code UNSPSC :
41116107
ID de substance PubChem :
329750972
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

promethazine

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

−20°C

Chaîne SMILES 

Cl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C

InChI

1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H

Clé InChI

XXPDBLUZJRXNNZ-UHFFFAOYSA-N

Informations sur le gène

human ... HRH1(3269)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Promethazine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Y0000797

Promethazine hydrochloride, European Pharmacopoeia (EP) Reference Standard

Y0000769

Promethazine impurity D, European Pharmacopoeia (EP) Reference Standard

P3400000

Promethazine hydrochloride, European Pharmacopoeia (EP) Reference Standard

1570029

Promethazine Related Compound B, United States Pharmacopeia (USP) Reference Standard

BP412

Promethazine hydrochloride, British Pharmacopoeia (BP) Reference Standard

BP778

Isopromethazine hydrochloride, British Pharmacopoeia (BP) Reference Standard

BP505

Promethazine sulfoxide, British Pharmacopoeia (BP) Reference Standard

PHR2777

Promethazine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 50 mg

Pictogrammes

CorrosionExclamation markEnvironment
GHS05,GHS07,GHS09

Mention d'avertissement

Danger

Mentions de danger

H302,H317,H318,H411

Classification des risques

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Mario Schietroma et al.
Journal of the American College of Surgeons, 220(5), 921-933 (2015-04-05)
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Shigeru Hishinuma et al.
Biochemical pharmacology, 91(2), 231-241 (2014-07-30)
Differential binding sites for first- and second-generation antihistamines were indicated on the basis of the crystal structure of human histamine H1 receptors. In this study, we evaluated differences between the thermodynamic driving forces of first- and second-generation antihistamines for human
Cheryl C Y Loh et al.
PloS one, 9(10), e110800-e110800 (2014-10-25)
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Jung Yeon Kim et al.
Biomedical chromatography : BMC, 29(3), 465-474 (2014-08-01)
The purpose of this study was to develop and validate an ultra-performance liquid chromatography method for simultaneous analysis of 20 antihistamines (illegal additives) in dietary supplements. The limits of detection and quantitation of the method ranged from 1.5 to 2.5
Andrew Curtright et al.
PloS one, 10(1), e0116766-e0116766 (2015-01-15)
Acute and chronic pain conditions are often debilitating, inflicting severe physiological, emotional and economic costs and affect a large percentage of the global population. However, the development of therapeutic analgesic agents based primarily on targeted drug development has been largely

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