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PHL89281

Silychristin

phyproof® Reference Substance

Synonyme(s) :

Silymarin II

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About This Item

Formule empirique (notation de Hill):
C25H22O10
Numéro CAS:
33889-69-9
Poids moléculaire :
482.44
Numéro MDL:
MFCD00883715
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

primary reference standard

Gamme de produits

phyproof® Reference Substance

Pureté

≥95.0% (HPLC)

Fabricant/nom de marque

PhytoLab

Application(s)

food and beverages

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

COc1cc(ccc1O)[C@@H]2Oc3c(O)cc(cc3[C@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O

InChI

1S/C25H22O10/c1-33-18-6-10(2-3-15(18)28)23-14(9-26)13-4-11(5-17(30)25(13)35-23)24-22(32)21(31)20-16(29)7-12(27)8-19(20)34-24/h2-8,14,22-24,26-30,32H,9H2,1H3/t14-,22+,23+,24-/m1/s1

Clé InChI

BMLIIPOXVWESJG-LMBCONBSSA-N

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Description générale

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application


  • Unveiling the healing properties of 2,3-dehydrosilychristin: A silymarin-derived flavonolignan with potent pharmacological activities, highlighting its significance in mitigating oxidative stress and enhancing cellular repair mechanisms in liver tissues (Tripathi et al., 2024).

  • Application of SNAP-tag-EGFR cell membrane chromatography model: This study identifies Silychristin as a key antitumor agent in Silybum marianum, detailing its role in targeted cancer therapies and its efficacy in inhibiting tumor cell proliferation (Zhang et al., 2024).

  • Pharmaceutical prospects of Silymarin for neurological patients: Provides an update on the neuroprotective properties of Silychristin, emphasizing its therapeutic potential in treating neurological disorders through modulation of oxidative stress and inflammation (Ranjan and Gautam, 2023).

  • Structural basis of Nrf2 activation by flavonolignans: Explores how Silychristin, as part of the Silymarin complex, activates the Nrf2 pathway, offering insights into its application in enhancing antioxidant responses at the molecular level (Bello, 2023).

  • Mechanistic Insights into the Pharmacological Significance of Silymarin: Reviews the broad pharmacological actions of Silychristin within the Silymarin complex, discussing its anti-inflammatory, antioxidant, and antifibrotic roles, which are pivotal for comprehensive healthcare applications (Wadhwa et al., 2022).

Autres remarques

This compound is commonly found in plants of the genus: silybum

Informations légales

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Conseils de prudence

P301 + P312 + P330

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
100575
82119
82122
124419085
112983074

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