U3750

Uridine

≥99%

• Synonyme(s) : 1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside
• Formule empirique (notation de Hill): C₉H₁₂N₂O₆
• Numéro CAS: 58-96-8
• Poids moléculaire : 244.20
• Numéro Beilstein : 754902
• Numéro CE : 200-407-5
• Numéro MDL: MFCD00006526
• Code UNSPSC : 41106305
• ID de substance PubChem : 24900640
• Nomenclature NACRES : NA.51

Propriétés

• Source biologique: synthetic (organic)
• Niveau de qualité: 200
• Pureté: ≥99%
• Forme: powder
• Pf: 163-167 °C (lit.)
• Solubilité: H₂O: 50 mg/mL, clear, colorless
• Chaîne SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
• Clé InChI: DRTQHJPVMGBUCF-XVFCMESISA-N
• Informations sur le gène: mouse ... Uck1(22245)

Description

Description générale

Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is synthesized in living organisms by de novo and salvage pathways.

Application

Uridine has been used:

• as a component of hippocampal neuron medium for culture of primary hippocampal neuron cells
• in uridine rescue experiments in mouse embryonic fibroblasts and human breast cancer cells
• in chase sequencing experiments

Actions biochimiques/physiologiques

Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine are implicated in insulin resistance.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)