SRP6081
TXNRD1 human
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Synonyme(s) :
GRIM-12, MGC9145, TR1, TRXR1, Thioredoxin reductase
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About This Item
Produits recommandés
Source biologique
human
Produit recombinant
expressed in E. coli
Pureté
≥95% (SDS-PAGE)
Forme
liquid
Puissance
0.48 units/mL
Poids mol.
55.7 kDa
Conditionnement
pkg of 100 μg
Numéro d'accès NCBI
Conditions d'expédition
dry ice
Température de stockage
−70°C
Informations sur le gène
human ... TXNRD1(7296)
Description générale
Thioredoxin reductase 1 (TNXRD1), cytoplasmic is an enzyme in humans that is encoded by the TXNRD1 gene. This gene encodes a member of the family of pyridine nucleotide oxidoreductases and is localized on human chromosome 12.
Actions biochimiques/physiologiques
Thioredoxin reductase 1 (TNXRD1) reduces thioredoxins as well as other substrates. It plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses flavin adenine dinucleotide (FAD) as a cofactor. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, acquired immune deficiency syndrome (AIDS), autoimmune diseases as well as bacterial infections and parasitic diseases.
Forme physique
0.5 mg/mL solution in PBS (pH 7.4) containing 20% glycerol.
Notes préparatoires
Centrifuge the vial prior to opening.
Autres remarques
MGSSHHHHHH SSGLVPRGSH MYDYDLIIIG GGSGGLAAAK EAAQYGKKVM VLDFVTPTPL GTRWGLGGTC VNVGCIPKKL MHQAALLGQA LQDSRNYGWK VEETVKHDWD RMIEAVQNHI GSLNWGYRVA LREKKVVYEN AYGQFIGPHR IKATNNKGKE KIYSAERFLI ATGERPRYLG IPGDKEYCIS SDDLFSLPYC PGKTLVVGAS YVALECAGFL AGIGLDVTVM VRSILLRGFD QDMANKIGEH MEEHGIKFIR QFVPIKVEQI EAGTPGRLRV VAQSTNSEEI IEGEYNTVML AIGRDACTRK IGLETVGVKI NEKTGKIPVT DEEQTNVPYI YAIGDILEDK VELTPVAIQA GRLLAQRLYA GSTVKCDYEN VPTTVFTPLE YGACGLSEEK AVEKFGEENI EVYHSYFWPL EWTIPSRDNN KCYAKIICNT KDNERVVGFH VLGPNAGEVT QGFAAALKCG LTKKQLDSTI GIHPVCAEVF TTLSVTKRSG ASILQAGC
Code de la classe de stockage
13 - Non Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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