SRP4809

Calretinin from mouse

recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC)

• Synonyme(s) : CR, Calb2, Calretinin, calbindin 2
• Code UNSPSC : 12352202

Propriétés

• Source biologique: mouse
• Produit recombinant: expressed in E. coli
• Pureté: ≥90% (HPLC); ≥90% (SDS-PAGE)
• Forme: solution
• Poids mol.: ~57 kDa
• Conditionnement: pkg of 5 μg
• Conditions de stockage: avoid repeated freeze/thaw cycles
• Impuretés: endotoxin, tested
• Numéro d'accès NCBI: Q08331
• Conditions d'expédition: dry ice
• Température de stockage: −70°C
• Informations sur le gène: mouse ... Calb2(12308)

Description

Description générale

Calretinin is a Ca²⁺-binding protein. It belongs to the EF-hand family. This gene is upregulated in reactive mesothelial cells and in malignant mesothelioma.
Recombinant mouse Calretinin protein is expressed from Escherichia coli and purified by proprietary chromatographic techniques.

Actions biochimiques/physiologiques

Calretinin is widely distributed in the brain and might be responsible for neural protection. It regulates calcium signaling in neurons. Absence of calretinin in mice negatively affects long-term potentiation, motor coordination and Purkinje cell activity.

Forme physique

50 ml (100 μg/ml) in 50 mM Tris-Acetate, pH 7.5, 1 mM EDTA, 20% Glycerol.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable