SML0511

GNF-5

≥98% (HPLC)

• Synonyme(s) : N-(2-Hydroxyethyl)-3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
• Formule empirique (notation de Hill): C₂₀H₁₇F₃N₄O₃
• Numéro CAS: 778277-15-9
• Poids moléculaire : 418.37
• Numéro MDL: MFCD16877246
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825520
• Nomenclature NACRES : NA.77

Propriétés

• Pureté: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Solubilité: DMSO: 10 mg/mL (clear solution)
• Température de stockage: 2-8°C
• Chaîne SMILES: OCCNC(=O)c1cccc(c1)-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2
• InChI: 1S/C20H17F3N4O3/c21-20(22,23)30-16-6-4-15(5-7-16)27-18-11-17(25-12-26-18)13-2-1-3-14(10-13)19(29)24-8-9-28/h1-7,10-12,28H,8-9H2,(H,24,29)(H,25,26,27)
• Clé InChI: IIQUYGWWHIHOCF-UHFFFAOYSA-N

Description

Actions biochimiques/physiologiques

GNF-5 is a BRC-Abl inhibitor.

Caractéristiques et avantages

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Abl page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Autres remarques

GNF-5 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the GNF-5 probe summary on the Chemical Probes Portal website.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3