SMB00806

7-Ketodeoxycholic acid

≥95% (HPLC)

• Synonyme(s) : 3α,12α-Dihydroxy-7-oxo-5β-cholanoic acid, 7-Oxo-3α,12α-dihydroxy-5β-cholanoic acid
• Formule empirique (notation de Hill): C₂₄H₃₈O₅
• Numéro CAS: 911-40-0
• Poids moléculaire : 406.56
• Code UNSPSC : 41141802
• Nomenclature NACRES : NA.28

Propriétés

• Pureté: ≥95% (HPLC)
• Forme: powder
• Conditionnement: pkg of 1 g; pkg of 50 mg
• Couleur: off-white to beige
• Pf: 193—198 °C
• Groupe fonctionnel: carboxylic acid; ketone
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• InChI: 1S/C24H38O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-18,20,22,25,27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,20+,22+,23+,24-/m1/s1
• Clé InChI: RHCPKKNRWFXMAT-RRWYKFPJSA-N

Description

Description générale

7-Ketodeoxycholic acid, categorized as a oxo-5beta-cholanic acid, is a bile acid derivative and a metabolite resulting from the degradation of the primary bile acid, cholic acid, by intestinal bacteria. Bile acids, natural steroid amphipathic compounds formed through cholesterol oxidation in the liver, play a crucial role in regulating lipid metabolism. They facilitate the digestion, absorption, and transport of lipids, lipid-soluble vitamins, and related molecules in the gastrointestinal tract. These bile acids also impact various aspects of cholesterol, glucose, and energy balance. However, in specific liver conditions such as intrahepatic cholestasis characterized by reduced bile flow, the accumulation of bile acids at elevated concentrations can lead to severe toxic effects. This makes 7-Ketodeoxycholic acid a compound of interest for biochemical and metabolomics research.

Application

7-Ketodeoxycholic acid finds application in metabolomics, biochemical and microbiome research.

Caractéristiques et avantages

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

Autres remarques

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Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable