SAB2701455

Anti-DYNC1LI1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonyme(s) : DNCLI1, DYNC1LI1, FLJ10219
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Espèces réactives: human, rat, mouse
• Technique(s): immunohistochemistry: suitable; immunoprecipitation (IP): suitable; indirect immunofluorescence: suitable; western blot: 1000-10000
• Numéro d'accès NCBI: AAI31621
• Numéro d'accès UniProt: Q9Y6G9
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Informations sur le gène: human ... DYNC1LI1(51143)

Description

Immunogène

Recombinant fragment corresponding to a region within amino acids 318 and 523 of DYNC1LI1 according to AAI31621

Application

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, IP: 1:100-1:500, WB: 1:1000-1:10000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Actions biochimiques/physiologiques

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Clause de non-responsabilité

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable