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SAB2500307

Sigma-Aldrich

Anti-DGAT1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Anti-ACAT related gene product 1, Anti-ARGP1, Anti-Acyl coenzyme A:cholesterol acyltransferase related gene 1, Anti-DGAT, Anti-Diacylglycerol O-acyltransferase homolog 1

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

goat

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

human, rat, canine, mouse

Technique(s)

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... DGAT1(8694)

Catégories apparentées

Description générale

Diacylglycerol O-acyltransferase 1 (DGAT1) is a 500kDa, hydrophobic protein, which is highly expressed in the skin, mammary gland, adipose tissue, small intestine and testis. The gene encoding it is localized on human chromosome 8q24.3.

Immunogène

Peptide with sequence C-QNSMKPFKDMDYS from the internal region of the protein sequence according to NP_036211.1.

Application

Anti-DGAT1 antibody produced in goat has been used in Western blotting.

Actions biochimiques/physiologiques

Diacylglycerol O-acyltransferase 1 (DGAT1) has a role in the biosynthesis of triglycerides. Mutations in the gene have been linked to congenital diarrhea and protein-losing enteropathy. DGAT1 is also associated with metabolic disorders like diabetes and obesity.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters
Chi-Liang
Journal of Lipid Research (2005)
Exclusion of the acyl CoA:diacylglycerol acyltransferase 1 gene (DGAT1) as a candidate for a fatty acid composition QTL on porcine chromosome 4
A. Mercade
Journal of Animal Breeding and Genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie (2005)
Prolonged silencing of diacylglycerol acyltransferase-1 induces a dedifferentiated phenotype in human liver cells.
Chang S
Journal of Cellular and Molecular Medicine (2016)
Identification and characterization of a novel DGAT1 missense mutation associated with congenital diarrhea.
Gluchowski NL
Journal of Lipid Research (2017)

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