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PRS4101

Sigma-Aldrich

Anti-Neuritin antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Anti-Cpg15, Anti-NRN1, Anti-Neuritin 1

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.43

Source biologique

rabbit

Niveau de qualité

100

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Poids mol.

predicted mol wt 16 kDa

Espèces réactives

mouse, human

Technique(s)

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

Numéro d'accès UniProt

Q9NPD7

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... NRN1(51299)

Description générale

Neuritin (NRN1) is a candidate plasticity associated gene, that is a member of the neurotrophic factor family. It is also known as CPG15. It is expressed in the liver, heart, lungs, skeletal muscle and other normal organs along with the nervous system. It is also expressed in gastric cancer tissues. It is mapped to chromosome 6p24-p2.

Immunogène

a 20 amino acid peptide from near the center of human neuritin.

Application

Anti-Neuritin has been used in immunohistochemistry and western blotting.

Actions biochimiques/physiologiques

In gastric cancer treatment, neuritin (NRN1) serves as a potential target. It also participates in the pathogenesis of tumors. It plays a major role in the nervous system and on the migration, senescence, proliferation, and viability of stem cells.

Liaison

The action of this antibody can be blocked using blocking peptide SBP4101.

Forme physique

Solution in phosphate buffered saline containing 0.02% sodium azide

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Effects of neuritin on the migration, senescence and proliferation of human bone marrow mesenchymal stem cells
Wang X, et al.
Cellular & Molecular Biology Letters, 20(3), 466-474 (2015)
Shuhei Kamada et al.
Frontiers in oncology, 11, 758503-758503 (2021-11-23)
Acquired therapeutic resistance and metastasis/recurrence remain significant challenge in advance renal cell carcinoma (RCC), thus the establishment of patient-derived cancer models may provide a clue to assess the problem. We recently characterized that neuritogenesis-related protein neuritin 1 (NRN1) functions as
Impact of Neuritin 1 (NRN1) polymorphisms on fluid intelligence in schizophrenia
Chandler D, et al.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 153B(2), 428-437 (2010)
Ming Yuan et al.
Oncology letters, 10(6), 3832-3836 (2016-01-21)
The aim of the present study was to investigate the expression of neuritin in gastric cancer tissues, in order to explore the association between the expression of neuritin and the occurrence and development of gastric cancer. Tissue specimens were collected
Overexpression of neuritin in gastric cancer
Yuan M, et al.
Oncology Letters, 10(6), 3832-3836 (2015)

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