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Merck
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N4037

Sigma-Aldrich

Anti-Netrin-G1a antibody produced in goat

affinity isolated antibody, lyophilized powder

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About This Item

Numéro MDL:
MFCD07784853
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

goat

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

lyophilized powder

Espèces réactives

mouse

Technique(s)

indirect ELISA: 0.5-1 μg/mL using recombinant mouse netrin-G1a
western blot: 0.1-0.2 μg/mL using recombinant mouse netrin-G1a

Numéro d'accès UniProt

Q8R4G0

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

mouse ... Ntng1(80883)

Description générale

Netrin-G1a (NTNG1) is also known as laminet 1. It is expressed in axons and is a trans-synaptic adhesion protein. NTNG1 is part of the glycosylphosphatidylinositol-anchored subfamily of the UNC-6/netrin family.

Spécificité

This antibody shows less than 2% cross-reactivity with rmNetrin-1, rhNetrin-2, and rhNetrin-4.

Immunogène

purified, insect cell line Sf 21-derived, recombinant mouse Netrin-G1a.

Actions biochimiques/physiologiques

Netrin-G1a (NTNG1) stimulates the outgrowth of axons in the thalamo-cortical region of the brain and helps to excite the post-synaptic regions.

Forme physique

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Hiroshi Matsukawa et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(47), 15779-15792 (2014-11-21)
Synaptic cell adhesion molecules are increasingly gaining attention for conferring specific properties to individual synapses. Netrin-G1 and netrin-G2 are trans-synaptic adhesion molecules that distribute on distinct axons, and their presence restricts the expression of their cognate receptors, NGL1 and NGL2
Kunio Yaguchi et al.
Molecular brain, 7, 19-19 (2014-03-20)
Higher brain function is supported by the precise temporal and spatial regulation of thousands of genes. The mechanisms that underlie transcriptional regulation in the brain, however, remain unclear. The Ntng1 and Ntng2 genes, encoding axonal membrane adhesion proteins netrin-G1 and
Elena Seiradake et al.
The EMBO journal, 30(21), 4479-4488 (2011-09-29)
Brain wiring depends on cells making highly localized and selective connections through surface protein-protein interactions, including those between NetrinGs and NetrinG ligands (NGLs). The NetrinGs are members of the structurally uncharacterized netrin family. We present a comprehensive crystallographic analysis comprising

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