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MAK065

Sigma-Aldrich

Lactate Assay Kit II

sufficient for 100 colorimetric tests

Synonyme(s) :

Lactic Acid Assay Kit

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About This Item

Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84

Utilisation

sufficient for 100 colorimetric tests

Application(s)

cosmetics
food and beverages

Méthode de détection

colorimetric

Maladie(s) pertinente(s)

endocrinological disorders, diabetes; cancer

Température de stockage

−20°C

Description générale

L(+)-Lactate is a metabolic compound formed in animals by the action of the enzyme Lactate Dehydrogenase. Lactate is produced in proliferating cells and during anaerobic conditions such as exercise. Abnormally high concentrations of lactate have been related to pathological conditions such as cancer, diabetes, and lactate acidosis. L(+)-Lactate is the major stereoisomer of lactate formed in human intermediary metabolism and is present in blood at levels of around 1-2 mmol/L. This kit provides a convenient means for detecting L(+)-Lactate in biological samples.

Application

Lactate Assay Kit II has been used to measure the levels of lactate in samples.

Adéquation

Suitable for detecting L(+)-Lactate in culture medium, fermentation medium, blood and cells.

Principe

Lactate concentration is determined by an enzyme assay, which results in a colorimetric (450 nm) product, proportional t the lactate present. There is no need of pretreatment or purification of samples. Typical sensitivities of detection are between 0.02-10 mM of lactate.

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Réf. du produit
Description
Tarif

Pictogrammes

Corrosion
GHS05

Mention d'avertissement

Danger

Mentions de danger

H314

Classification des risques

Eye Dam. 1 - Skin Corr. 1B

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Metabolic engineering of Methanosarcina acetivorans for lactate production from methane
McAnulty M J, et al.
Biotechnology and Bioengineering, 114(4), 852-861 (2017)
DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders.
Jouroukhin Y, et al.
Translational Psychiatry, 8(1), 76-76 (2018)
Camaron R Hole et al.
Nature communications, 10(1), 2955-2955 (2019-07-06)
Dendritic cells (DCs), a vital component of the innate immune system, are considered to lack antigen specificity and be devoid of immunological memory. Strategies that can induce memory-like responses from innate cells can be utilized to elicit protective immunity in
Satyendra C Tripathi et al.
Cancer research, 77(16), 4414-4425 (2017-06-25)
Despite favorable responses to initial therapy, small-cell lung cancer (SCLC) relapse occurs within a year and exhibits resistance to multiple drugs. Because of limited accessibility of patient tissues for research purposes, SCLC patient-derived xenografts (PDX) have provided the best opportunity
Yan Jouroukhin et al.
Translational psychiatry, 8(1), 76-76 (2018-04-13)
Our knowledge of how genetic risk variants contribute to psychiatric disease is mainly limited to neurons. However, the mechanisms whereby the same genetic risk factors could affect the physiology of glial cells remain poorly understood. We studied the role of
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