M4280
Anti-Mouse IgG (Fc specific) antibody produced in goat
2.0 mg/mL, affinity isolated antibody
Synonyme(s) :
Anti Mouse Fc Antibody, Anti Mouse Fc Antibody - Anti-Mouse IgG (Fc specific) antibody produced in goat
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About This Item
Produits recommandés
Source biologique
goat
Conjugué
unconjugated
Forme d'anticorps
affinity isolated antibody
Type de produit anticorps
secondary antibodies
Clone
polyclonal
Concentration
2.0 mg/mL
Technique(s)
indirect ELISA: 1:20,000
Conditions d'expédition
dry ice
Température de stockage
−20°C
Modification post-traductionnelle de la cible
unmodified
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Description générale
Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. Immunoglobulins have two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.
Immunogène
Fc fragment of IgG purified from mouse.
Application
Anti-Mouse IgG (Fc specific) antibody produced in goat has been used in:
- enzyme-linked immunosorbent assay (ELISA)
- flow cytometry
- immunoprecipitation
- immunoblotting
Actions biochimiques/physiologiques
IgG antibody plays a crucial role in humoral immune responses such as complement activation, phagocytosis, placental transport and cell surface-receptor binding. The antigen binding activity is mediated by the variable Fab region of IgG antibodies, whereas the effector activities are stimulated by the Fc domain. Anti-mouse IgG (Fc specific) antibody can be used to detect the optimal capture agents.
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. It mainly helps in immune defense. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.
Autres remarques
Antibody adsorbed with bovine, equine and human serum proteins.
Forme physique
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Notes préparatoires
Adsorbed to reduce background staining with bovine, horse or human samples.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
nwg
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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