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I6005

Sigma-Aldrich

myo-Inositol hexasulfate hexapotassium salt

Synonyme(s) :

Inositol hexakissulfate, InsS6

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About This Item

Formule linéaire :
C6H6O24S6K6
Numéro CAS:
28434-25-5
Poids moléculaire :
889.08
Numéro MDL:
MFCD00055894
Code UNSPSC :
12352201
ID de substance PubChem :
24896081

Température de stockage

−20°C

Chaîne SMILES 

[K].OS(=O)(=O)OC1C(OS(O)(=O)=O)C(OS(O)(=O)=O)C(OS(O)(=O)=O)C(OS(O)(=O)=O)C1OS(O)(=O)=O

InChI

1S/C6H12O24S6.K.H/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;/h1-6H,(H,7,8,9)(H,10,11,12)(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24);;

Clé InChI

JYVHCOUFXHFSLT-UHFFFAOYSA-N

Actions biochimiques/physiologiques

InsS6 has a molecular footprint and negative surface charge that is similar to that of phytic acid (InsP6), but with lower biological activity. It is used as a control in studies of the cellular actions of phytic acid. It is also a competitive inhibitor of Aspergillus phytase.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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R Kojima et al.
Japanese journal of pharmacology, 53(3), 347-358 (1990-07-01)
We examined the protective effect of inositol hexasulfate (IS6) against tobramycin (TOB)-induced nephrotoxicity. In the electrophoretic analysis, TOB alone and IS6 alone were observed as single spots on the cathode and anode sides, respectively. However, in the mixture of TOB
G Oshima
Thrombosis research, 58(3), 243-250 (1990-05-01)
Thrombin-clotting time of fibrinogen was delayed by inositol hexasulfate (IHS). Clotting time of the recalcified plasma was also delayed by IHS. Moreover, when IHS was intravenously injected into anesthetized male rabbits (0.11 mmoles/kg), it delayed clotting time of the recalcified
N M Dean et al.
The Biochemical journal, 250(2), 493-500 (1988-03-01)
Previous studies demonstrated a multiplicity of isomers of inositol phosphates in GH3 rat pituitary tumour cells. In order to determine their origin, we have investigated the metabolism of radiolabelled inositol phosphates (IPn) in GH3 cell homogenates by using h.p.l.c. I(1,4,5)P3
Sonali P Jog et al.
Archives of biochemistry and biophysics, 440(2), 133-140 (2005-07-30)
Phytases catalyze the hydrolysis of phytic acid (InsP6, myo-inositol hexakisphosphate), the most abundant inositol phosphate in cells. In cereal grains and legumes, it constitutes 3-5% of the dry weight of seeds. The inability of humans and monogastric animals such as
M Guzmán-Casado et al.
International journal of biological macromolecules, 28(4), 305-313 (2001-04-20)
The interaction of an amino-terminal-truncated 139 amino-acids form of human acidic fibroblast growth factor with myo-inositol hexasulphate and low molecular weight (3500 g mol(-1)) heparin has been studied by isothermal titration calorimetry, differential scanning calorimetry and Fourier transform infrared spectroscopy.
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