I2250

Indole-5-carboxylic acid

~95% (TLC)

• Synonyme(s) : 5-Carboxyindole
• Formule empirique (notation de Hill): C₉H₇NO₂
• Numéro CAS: 1670-81-1
• Poids moléculaire : 161.16
• Beilstein: 124391
• Numéro CE : 216-799-6
• Numéro MDL: MFCD00005678
• Code UNSPSC : 12352100
• ID de substance PubChem : 24895968

Propriétés

• Essai: ~95% (TLC)
• Pf: 211-213 °C (lit.)
• Température de stockage: −20°C
• Chaîne SMILES: OC(=O)c1ccc2[nH]ccc2c1
• InChI: 1S/C9H7NO2/c11-9(12)7-1-2-8-6(5-7)3-4-10-8/h1-5,10H,(H,11,12)
• Clé InChI: IENZCGNHSIMFJE-UHFFFAOYSA-N

Description

Application

• Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators
• Reactant for preparation of indolyl-quinolines via metal- and solvent-free autoxidative coupling reaction
• Reactant for preparation of anthranilic acids using bromamine-B oxidant and palladium chloride catalyst
• Reactant for synthesis of indirubin derivatives
• Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway
• Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)