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HPA058448

Sigma-Aldrich

Anti-TNNT1 antibody produced in rabbit

enhanced validation

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Synonyme(s) :

Anti-ANM, Anti-FLJ98147, Anti-MGC104241, Anti-NEM5, Anti-STNT, Anti-TNT, Anti-TNTS

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About This Item

Code UNSPSC :
12352203
Numéro HPA (Human Protein Atlas):
HPA058448
Nomenclature NACRES :
NA.43

Source biologique

rabbit

Niveau de qualité

100

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Gamme de produits

Prestige Antibodies® Powered by Atlas Antibodies

Forme

buffered aqueous glycerol solution

Espèces réactives

human

Validation améliorée

orthogonal RNAseq
Learn more about Antibody Enhanced Validation

Technique(s)

immunohistochemistry: 1:500- 1:1000

Séquence immunogène

EEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGE

Numéro d'accès UniProt

P13805

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... TNNT1(7138)

Description générale

Troponin T1 (TNNT1) is located on human chromosome 19q13.4. The encoded protein is composed of 261 amino acids and is expressed specifically in slow skeletal muscle.

Immunogène

troponin T type 1 (skeletal, slow)

Application

Anti-TNNT1 antibody has been used in immunohistochemical staining.

Actions biochimiques/physiologiques

Troponin T1 (TNNT1) plays a vital role in calcium regulation of striated muscle contraction and relaxation. Mutation in the gene is associated with the development of nemaline myopathy.

Caractéristiques et avantages

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

Liaison

Corresponding Antigen APREST87837

Forme physique

Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.

Informations légales

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Joshua S Clayton et al.
Acta neuropathologica communications, 8(1), 142-142 (2020-08-21)
Ovine congenital progressive muscular dystrophy (OCPMD) was first described in Merino sheep flocks in Queensland and Western Australia in the 1960s and 1970s. The most prominent feature of the disease is a distinctive gait with stiffness of the hind limbs
Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells.
Ware C B, et al.
Cell Stem Cell, 4(4), 359-369 (2009)
Alice Rannou et al.
Molecular therapy. Methods & clinical development, 18, 446-463 (2020-07-23)
Myocardial infarction is one of the leading causes of mortality and morbidity worldwide. Whereas transplantation of several cell types into the infarcted heart has produced promising preclinical results, clinical studies using analogous human cells have shown limited structural and functional
TNNT1, TNNT2, and TNNT3: Isoform Genes, Regulation, and Structure-Function Relationships.
Wei B and Jin J P
Gene, 582(1), 1-13 (2016)
Cecilia Lindskog et al.
BMC genomics, 16, 475-475 (2015-06-26)
To understand cardiac and skeletal muscle function, it is important to define and explore their molecular constituents and also to identify similarities and differences in the gene expression in these two different striated muscle tissues. Here, we have investigated the

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