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HPA049832

Sigma-Aldrich

Anti-NTN4 antibody produced in rabbit

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Synonyme(s) :

Anti-netrin 4

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About This Item

Code UNSPSC :
12352203
Numéro HPA (Human Protein Atlas):
HPA049832
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Gamme de produits

Prestige Antibodies® Powered by Atlas Antibodies

Forme

buffered aqueous glycerol solution

Espèces réactives

human

Technique(s)

immunohistochemistry: 1:50- 1:200

Séquence immunogène

AGVSSRCEKACNPRMGNLALGRKLWADTTCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAEDVHRE

Numéro d'accès UniProt

Q9HB63

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... NTN4(59277)

Catégories apparentées

Description générale

NTN4 (netrin-4) belongs to the axon guidance molecule family. It is expressed in the inner lamina II (lamina IIi) neurons of the dorsal horn. It is located on chromosome 12q22.

Immunogène

netrin 4 recombinant protein epitope signature tag (PrEST)

Application

Anti-NTN4 antibody has been used in immunohistochemistry.

Actions biochimiques/physiologiques

NTN4 (netrin-4) is responsible for increasing the mechanical and thermal sensitivity throughout neuropathic or inflammatory pain. It is actively involved in angiogenesis, lung branching, and salivary gland formation.

Caractéristiques et avantages

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

Liaison

Corresponding Antigen APREST85291

Forme physique

Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.

Informations légales

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Netrin-4 regulates thalamocortical axon branching in an activity-dependent fashion.
Hayano Y, et al.
Proceedings of the National Academy of Sciences of the USA, 111(42), 15226-15231 (2014)
Gene expressions and copy numbers associated with metastatic phenotypes of uterine cervical cancer.
Lyng H, et al.
BMC Genomics, 7:268 (2006)
Dorsal horn interneuron-derived Netrin-4 contributes to spinal sensitization in chronic pain via Unc5B.
Hayano Y, et al.
The Journal of Experimental Medicine, 213(13), 2949-2966 (2016)
Lars Harbaum et al.
American journal of respiratory and critical care medicine, 205(12), 1449-1460 (2022-04-09)
Rationale: Pulmonary arterial hypertension (PAH) is characterized by structural remodeling of pulmonary arteries and arterioles. Underlying biological processes are likely reflected in a perturbation of circulating proteins. Objectives: To quantify and analyze the plasma proteome of patients with PAH using
Yu-Hao Huang et al.
International journal of biological sciences, 20(1), 265-279 (2024-01-03)
Endometrial carcinoma (EC) is a common type of uterine cancer in developed countries, originating from the uterine epithelium. The incidence rate of EC in Taiwan has doubled from 2005. Cancer stem cells (CSCs) are a subpopulation of cancer cells that
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