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COO/COA

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H2644

1-O-Palmityl-2-O-methyl-rac-glycerol

Name: 1-O-Palmityl-2-O-methyl-<I>rac</I>-glycerol
Brand: SIGMA

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About This Item

Formule empirique (notation de Hill):

C₂₀H₄₂O₃

Numéro CAS:

111188-59-1

Poids moléculaire :

330.55

Numéro MDL:

MFCD00079344

Code UNSPSC :

12352200

Température de stockage

−20°C

Chaîne SMILES

CCCCCCCCCCCCCCCCOCC(CO)OC

Code de la classe de stockage

13 - Non Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

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Phospholipid metabolism in bradykinin-stimulated human fibroblasts. II. Phosphatidylcholine breakdown by phospholipases C and D; involvement of protein kinase C.

W J van Blitterswijk et al.

The Journal of biological chemistry, 266(16), 10344-10350 (1991-06-05)

Bradykinin (BK) and phorbol 12-myristate 13-acetate (PMA) both stimulate the hydrolysis of phosphatidylcholine (PC) in human fibroblasts, resulting in the formation of phosphatidic acid (PA) and diacylglycerol (DG) (Van Blitterswijk, W.J., Hilkmann, H., de Widt, J., and Van der Bend

Activation of guinea pig eosinophil respiratory burst by leukotriene B4: role of protein kinase C.

K F Rabe et al.

Fundamental & clinical pharmacology, 6(8-9), 353-358 (1992-01-01)

Leukotriene B4 (LTB4) and the protein kinase C activator, 4-beta-phorbol dibutyrate (PDBu), both induced a pronounced and concentration-dependent stimulation of hydrogen peroxide (H2O2) generation by purified guinea pig peritoneal eosinophils in the concentration range 1 nM-1 microM. The LTB4 response

Phosphatidylinositol transfer proteins and protein kinase C make separate but non-interacting contributions to the phosphorylation state necessary for secretory competence in rat mast cells.

J A Pinxteren et al.

The Biochemical journal, 356(Pt 1), 287-296 (2001-05-05)

Mast cells permeabilized by streptolysin O undergo exocytosis when stimulated with Ca(2+) and guanosine 5'-[gamma-thio]triphosphate but become progressively refractory to this stimulus if it is delayed. This run-down of responsiveness occurs over a period of 20-30 min, during which the

1-O-hexadecyl-2-Q-methylglycerol, a novel inhibitor of protein kinase C, inhibits the respiratory burst in human neutrophils.

I M Kramer et al.

The Journal of biological chemistry, 264(10), 5876-5884 (1989-04-05)

To assess the role of protein kinase C (Ca2+/phospholipid-dependent enzyme) in the activation of the human neutrophil respiratory burst, we have utilized an ether lipid of the type 1-O-alkyl-2-O-methylglycerol (AMG), recently shown to be an inhibitor of this kinase. AMG-C16

Differentiation-promoting effect of 1-O (2 methoxy) hexadecyl glycerol in human colon cancer cells.

H Wang et al.

Journal of cellular physiology, 178(2), 173-178 (1999-02-27)

Alkylglycerols are naturally occurring bioactive ether lipids found in great abundance in the livers of many marine species. In this study, we evaluated the differentiation-promoting potential of a methoxy substituted alkylglycerol--1-O (2 methoxy) hexadecyl glycerol (MHG)--to promote a more benign

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