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GW22651

Sigma-Aldrich

Anti-Spondin-1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

chicken

Niveau de qualité

200

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

human, rat, mouse

Fabricant/nom de marque

Genway 15-288-22651

Technique(s)

western blot: suitable

Numéro d'accès NCBI

NP_006099.1

Numéro d'accès UniProt

Q9HCB6

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... SPON1(10418)

Immunogène

Immunogen Sequence: GI # 24307905, sequence 549-807
Recombinant spondin 1, extracellular matrix protein

Application

Anti-Spondin-1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Actions biochimiques/physiologiques

Spondin-1 (also known as F-spondin) is a protein encoded by the SPON1 gene in humans. It is an extracellular matrix protein that mediates axon guidance during neuronal development and consists of an N-terminal domain called as reelin-N domain. F-spondin highly expressing human periodontal ligament (HPL) cells show similar phenotype of cementoblasts. It acts as a promoting factor for cementoblastic differentiation.

Forme physique

Solution in phosphate buffered saline containing 0.02% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Kemin Tan et al.
Journal of molecular biology, 381(5), 1213-1223 (2008-07-08)
The extracellular matrix protein F-spondin mediates axon guidance during neuronal development. Its N-terminal domain, termed the reelin-N domain, is conserved in F-spondins, reelins, and other extracellular matrix proteins. In this study, a recombinant human reelin-N domain has been expressed, purified
Masae Kitagawa et al.
Biochemical and biophysical research communications, 349(3), 1050-1056 (2006-09-13)
Cementum is a mineralized tissue produced by cementoblasts covering the roots of teeth that provides for the attachment of periodontal ligament to roots and surrounding alveolar bone. To study the mechanism of proliferation and differentiation of cementoblasts is important for

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