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GW22383A

Sigma-Aldrich

Anti-PNLIPRP2 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

Code UNSPSC :
12352203

Source biologique

chicken

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

human, rat, mouse

Fabricant/nom de marque

Genway 15-288-22383A

Technique(s)

western blot: suitable

Numéro d'accès NCBI

NP_005387.1

Numéro d'accès UniProt

P54317

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

human ... PNLIPRP2(5408)

Immunogène

Immunogen Sequence: GI # 4885555, sequence 16-139
Recombinant pancreatic lipase-related protein 2

Application

Anti-PNLIPRP2 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Actions biochimiques/physiologiques

PNLIPRP2 (pancreatic lipase-related protein 2) is also know as PLRP2 . It can digest fats in human milk and formula. In mice, it is essential for fat digestion, and in humans, its role in fat digestion is unclear. IL-4 induces PLRP2 in cytotoxic T lymphocytes (CTLs). PLRP2 can help in killing tumor cells and is alone required for lipid-dependent cytotoxicity mediated by cytotoxic T lymphocytes (CTLs).

Forme physique

Solution in phosphate buffered saline containing 0.02% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Karin Johnson et al.
Pediatric research, 74(2), 127-132 (2013-06-05)
Dietary fats must be digested into fatty acids and monoacylglycerols prior to absorption. In adults, colipase-dependent pancreatic triglyceride lipase (PTL) contributes significantly to fat digestion. In newborn rodents and humans, the pancreas expresses low levels of PTL. In rodents, a
Bryce N Alves et al.
Cell biochemistry and function, 27(5), 296-308 (2009-06-24)
IL-4 induces a lipase, pancreatic lipase related protein 2 (PLRP2), in cytotoxic T lymphocytes (CTLs). Because PLRP2 in semen can mediate lipid-dependent toxicity to sperm, we questioned whether CTL-derived PLRP2 could support similar cytotoxicity toward tumor cells. Recombinant PLRP2 was
Xunjun Xiao et al.
The Journal of biological chemistry, 286(30), 26353-26363 (2011-06-10)
In newborn mice, PLRP2 is essential for fat digestion. In human infants, the role of PLRP2 in fat digestion is unclear, as it has poor activity against long-chain triglycerides in vitro. Also, many infants carry a genetic polymorphism resulting in

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