Accéder au contenu
Merck
Toutes les photos(1)

Documents

GW21070

Sigma-Aldrich

Anti-CXCL9 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Anti-Small inducible cytokine B9

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme


About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

chicken

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

human

Fabricant/nom de marque

Genway 15-288-21070

Technique(s)

western blot: suitable

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... CXCL9(4283)

Description générale

CXCL9 (chemokine (C-X-C motif) ligand 9) is a ligand for chemokine (C-X-C motif) receptor 3 (CXCR3), which is inducible by interferon-γ. It is expressed on CD4+ Th1 cells and CD8+ cytotoxic T cells. It is also secreted by neutrophils and macrophages. It acts as a chemoattractant for activated T-lymphocytes.

Immunogène

Immunogen Sequence: GI # 4505187, sequence 21-64
Recombinant small inducible cytokine B9

Application

Anti-CXCL9 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Actions biochimiques/physiologiques

Chemokine (C-X-C motif) ligand 9 (CXCL9) is more abundantly expressed in tumors cells than in normal epithelium. CXCL9 is associated with tumor and aggressiveness of NPC (nasopharyngeal carcinoma) tumors and the serum level of this may be useful as a prognostic indicator. In NPC tumors, serum concentration is found to be significantly higher. CXCL9 can act as a potential therapeutic target for human CGGN (Cryoglobulinemic glomerulonephritis).

Forme physique

Solution in phosphate buffered saline containing 0.02% sodium azide.

Not finding the right product?  

Try our Outil de sélection de produits.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Carrie L Kitko et al.
Blood, 123(5), 786-793 (2013-12-24)
There are no validated biomarkers for chronic GVHD (cGVHD). We used a protein microarray and subsequent sequential enzyme-linked immunosorbent assay to compare 17 patients with treatment-refractory de novo-onset cGVHD and 18 time-matched control patients without acute or chronic GVHD to
J Kowalewska et al.
Advances in medical sciences, 58(2), 394-400 (2013-10-03)
Cryoglobulinemic glomerulonephritis (CGGN) is a type of membranoproliferative glomerulonephritis (MPGN) that develops in patients with systemic cryoglobulinemia. To date the exact pathogenesis of CGGN remains unclear. It has been suggested that macrophages may be significant contributors to the glomerular injury
Li-Jen Hsin et al.
PloS one, 8(11), e80052-e80052 (2013-11-28)
The aim of this cohort study was to examine the role of the chemokine (C-X-C motif) ligand 9 (CXCL9) on nasopharyngeal carcinoma (NPC). Sera from 205 NPC patients and 231 healthy individuals, and 86 NPC tumor samples were enrolled. CXCL9

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique