G6646
Growth Hormone Releasing Factor rat
≥95% (HPLC), powder, synthetic
Synonyme(s) :
GRF
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About This Item
Formule empirique (notation de Hill):
C225H361N77O66S
Numéro CAS:
Poids moléculaire :
5232.82
Numéro MDL:
Code UNSPSC :
12352200
Source biologique
synthetic
Pureté
≥95% (HPLC)
Forme
powder
Composition
Peptide content, ~70%
Numéro d'accès UniProt
Température de stockage
−20°C
Clé InChI
ORNDKVCWLUZAQL-FOWIMTFFSA-N
Informations sur le gène
rat ... Ghrh(29446)
Amino Acid Sequence
His-Ala-Asp-Ala-Ile-Phe-Thr-Ser-Ser-Tyr-Arg-Arg-Ile-Leu-Gly-Gln-Leu-Tyr-Ala-Arg-Lys-Leu-Leu-His-Glu-Ile-Met-Asn-Arg-Gln-Gln-Gly-Glu-Arg-Asn-Gln-Glu-Gln-Arg-Ser-Arg-Phe-Asn
Actions biochimiques/physiologiques
Hypothalamic peptide that stimulates release of somatotropin from anterior pituitary
Code de la classe de stockage
13 - Non Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
Certificats d'analyse (COA)
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J Kraicer et al.
Canadian journal of physiology and pharmacology, 69(2), 181-184 (1991-02-01)
The purpose of this study was to characterize the biological activity of the synthetic rat growth hormone releasing factor analogue rGRF(1-29)NH2 and to compare its action on growth hormone (GH) release to that of authentic rGRF(1-43)OH. We first compared the
L G Frigeri et al.
Endocrinology, 122(6), 2940-2945 (1988-06-01)
Treatment of obese yellow Avy/A mice with the human GH (hGH) peptide hGH-(1-43) enhanced the in vitro sensitivity of their adipose tissue to insulin. Insulin-stimulated glucose oxidation, as determined by measurement of 14CO2 production, was enhanced 106% after administration of
T Audhya et al.
Proceedings of the National Academy of Sciences of the United States of America, 82(9), 2970-2974 (1985-05-01)
Polyclonal antibodies to synthetic human pancreatic growth hormone-releasing factor [hpGRF(1-44)NH2] and rat hypothalamic growth hormone-releasing factor [rhGRF(1-43)OH] were produced in rabbits by injecting these weak immunogens, coupled to thyroglobulin and emulsified with complete Freund's adjuvant in the presence of activated
N Deslauriers et al.
Regulatory peptides, 20(3), 261-271 (1988-03-01)
We studied the effect of rat growth hormone-releasing factor-(1-43) acid, rGRF(1-43)OH, on the long-term secretion of rat growth hormone (rGH) in dispersed primary cultured cells of rat anterior pituitaries over a period of 7 days or longer. Results of the
J Spiess et al.
Nature, 303(5917), 532-535 (1983-06-09)
The importance of the hypothalamus in the regulation of growth hormone (GH) secretion from the adenohypophysis has been supported by experimental and clinical evidence. It has been observed that GH secretion is in part controlled by hypothalamic GH release-inhibiting factors
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