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D1156

Sigma-Aldrich

N,N-Dimethylglycine

≥99%, suitable for ligand binding assays

Synonyme(s) :

(Dimethylamino)acetic acid

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About This Item

Formule linéaire :
(CH3)2NCH2COOH
Numéro CAS:
1118-68-9
Poids moléculaire :
103.12
Numéro Beilstein :
1700261
Numéro CE :
214-267-8
Numéro MDL:
MFCD00004283
Code UNSPSC :
12352209
eCl@ss :
32160406
ID de substance PubChem :
24893366
Nomenclature NACRES :
NA.26

product name

N,N-Dimethylglycine, ≥99%

Pureté

≥99%

Forme

powder

Technique(s)

ligand binding assay: suitable

Couleur

white to off-white

Pf

178-182 °C (lit.)

Application(s)

peptide synthesis

Chaîne SMILES 

CN(C)CC(O)=O

InChI

1S/C4H9NO2/c1-5(2)3-4(6)7/h3H2,1-2H3,(H,6,7)

Clé InChI

FFDGPVCHZBVARC-UHFFFAOYSA-N

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Actions biochimiques/physiologiques

N,N-Dimethylglycine (DMG) is a natural N-methylated glycine that is used in comparative analysis with other N-methylated glycines such as sarcosine and βine. N,N-Dimethylglycine is used in the development of glycine-based ionic liquids and emulsifiers. N,N-Dimethylglycine is potentially useful as a biomarker of protein degradation in COPD patients. DMG is used as a substrate to identify, differentiate and characterize amino acid methyltransferase(s).

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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S H Moolenaar et al.
Clinical chemistry, 45(4), 459-464 (1999-04-02)
A38-year-old man presented with a history of fish odor (since age 5) and unusual muscle fatigue with increased serum creatine kinase. Our aim was to identify the metabolic error in this new condition. We used 1H NMR spectroscopy to study
Baljit K Ubhi et al.
The European respiratory journal, 40(2), 345-355 (2011-12-21)
There is a paucity of biomarkers for chronic obstructive pulmonary disease (COPD). Metabolomics were applied to a defined COPD patient cohort from the ECLIPSE study (Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points). Results were correlated with accepted biomarkers
Ali A Moazzami et al.
The Journal of nutrition, 141(12), 2126-2132 (2011-10-21)
Prostate cancer (PC) is the most common cancer in the Western world and the second most important cancer causing male deaths, after lung cancer, in the United States and Britain. Lifestyle and dietary changes are recommended for men diagnosed with
D Vanhauteghem et al.
Amino acids, 43(1), 245-253 (2011-09-14)
The current study first investigates the emulsifying potential of glycine and its N-methylated derivatives N-methylglycine (sarcosine), N,N-dimethylglycine (DMG) and N,N,N-trimethylglycine (betaine) under varying pH conditions. Subsequently, the effect of these test compounds on the membrane integrity of enterotoxigenic Escherichia coli
Isabelle D Kalmar et al.
The British journal of nutrition, 107(11), 1635-1644 (2011-09-21)
N,N-Dimethylglycine (DMG) is a tertiary amino acid that naturally occurs as an intermediate metabolite in choline-to-glycine metabolism. The objective of the present trial was to evaluate tolerance, safety and bioaccumulation of dietary DMG in broilers when supplemented at 1 g
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