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Merck
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Principaux documents

A3612

Sigma-Aldrich

Ceftizoxime sodium salt

Synonyme(s) :

Ceftizoxime sodium

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About This Item

Formule linéaire :
C13H12N5NaO5S2
Numéro CAS:
68401-82-1
Poids moléculaire :
405.38
Code UNSPSC :
51284149
Nomenclature NACRES :
NA.85

Essai

≥98% (HPLC)

Forme

solid

Couleur

white to faint yellow

Solubilité

DMSO: 1 mg/mL

Spectre d'activité de l'antibiotique

Gram-negative bacteria
Gram-positive bacteria

Mode d’action

cell wall synthesis | interferes

Température de stockage

−20°C

InChI

1S/C13H13N5O5S2.Na/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18;/h2,4,8,11H,3H2,1H3,(H2,14,15)(H,16,19)(H,21,22);/q;+1/p-1/b17-7-;/t8-,11-;/m1./s1

Clé InChI

ADLFUPFRVXCDMO-LIGXYSTNSA-M

Actions biochimiques/physiologiques

Ceftizoxime is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.

Conditionnement

50mg

Autres remarques

Keep container tightly closed in a dry and well-ventilated place.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
072M4138V
14120705
108M4838V

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Soraya Maria Zandim Maciel Dias Ferreira et al.
Bioorganic & medicinal chemistry letters, 22(14), 4605-4608 (2012-06-26)
Osteomyelitis is an infectious disease located in the bone or bone marrow. Long-circulating and pH-sensitive liposomes containing a technetium-99m-labeled antibiotic, ceftizoxime, (SpHL-(99m)Tc-CF) were developed to identify osteomyelitis foci. Biodistribution studies and scintigraphic images of bone infection or non infection-bearing rats
Bashier Osman et al.
BMC research notes, 6, 57-57 (2013-02-12)
A prophylactic antibiotic is recommended to reduce infection-related complication following cesarean delivery. There is a current debate on the time of prophylactic antibiotic in cesarean delivery. An opened randomized, controlled clinical trial was conducted at Soba hospital, Sudan to investigate
M Jayahar Bharathi et al.
Ophthalmic research, 47(1), 52-56 (2011-07-02)
To evaluate resistances mediated by extended-spectrum β-lactamases (ESBLs) and AmpC β-lactamases among Gram-negative bacteria recovered from ocular infections. As per the Clinical Laboratory Standards Institute M100-S-16 document, a total of 135 Gram-negative bacilli were recovered from ocular specimens and were
Thomas M Hooton et al.
JAMA, 307(6), 583-589 (2012-02-10)
Although fluoroquinolones remain the most reliable urinary antimicrobial, resistance rates have increased and effective fluoroquinolone-sparing antimicrobials are needed. To determine whether cefpodoxime is noninferior to ciprofloxacin for treatment of acute cystitis. Randomized, double-blind trial of 300 women aged 18 to
Peymaneh Alizadeh Taheri et al.
Acta medica Iranica, 49(8), 499-503 (2011-10-20)
Neonatal sepsis, a life-threatening condition, presents with non-specific clinical manifestations and needs immediate empirical antimicrobial therapy. Choosing an appropriate antibiotic regimen covering the most probable pathogens is an important issue. In this study we compared the effectiveness of ceftizoxime and
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