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A126

Sigma-Aldrich

(±)-HA-966

Synonyme(s) :

(±)-3-Amino-1-hydroxy-2-pyrrolidone

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About This Item

Formule empirique (notation de Hill) :
C4H8N2O2
Numéro CAS:
1003-51-6
Poids moléculaire :
116.12
Numéro MDL:
MFCD00069208
Code UNSPSC :
12352200
ID de substance PubChem :
24890516

Chaîne SMILES 

NC1CCN(O)C1=O

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Conseils de prudence

P261 - P305 + P351 + P338

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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Lot/Batch Number

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Valéria Martinez et al.
Pain, 99(3), 537-545 (2002-10-31)
Systemic opioid dosing until adequate analgesia in neuropathic pain may involve intolerable and untreatable side effects. Peripheral opioid receptor mechanisms may participate in the antinociceptive effect of systemic morphine. We evaluated the effect of peripherally injected morphine alone, and the
J Klein et al.
Pharmacopsychiatry, 36 Suppl 1, S78-S83 (2003-09-18)
We have previously shown that hypoxia and N-methyl-D-aspartate (NMDA) receptor activation induce breakdown of choline-containing phospholipids in rat hippocampus, a process which is mediated by calcium influx and phospholipase A (2) activation. Bilobalide, a constituent of Ginkgo biloba, inhibited this
Frédéric Adam et al.
Neuropharmacology, 51(2), 191-202 (2006-05-23)
N-methyl-D-aspartate (NMDA) receptors are widely involved in opioid tolerance. However, it is less clear whether NMDA receptor antagonists reverse already-established tolerance and whether the intensity of the nociceptive stimulus influences morphine tolerance. Three days after implantation of morphine or control
Joanne E Nash et al.
Movement disorders : official journal of the Movement Disorder Society, 17(3), 455-466 (2002-07-12)
Treatments for Parkinson's disease based on replacement of lost dopamine have several problems. Following loss of dopamine, enhanced N-methyl-D-aspartate (NMDA) receptor-mediated transmission in the striatum is thought to be part of the cascade of events leading to the generation of
Melissa Nunnink et al.
Pharmacology, biochemistry, and behavior, 87(3), 321-330 (2007-06-15)
Conditioned taste aversion (CTA) is a form of associative learning in which the pairing of a taste with a toxin causes an animal to avoid the taste. NMDA receptor mediated neurotransmission has been implicated in CTA, but the role of
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