A0232

Alfuzosin hydrochloride

≥98% (HPLC), solid

• Synonyme(s) : N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamide hydrochloride, Uroxatral hydrochloride
• Formule empirique (notation de Hill): C₁₉H₂₇N₅O₄ · HCl
• Numéro CAS: 81403-68-1
• Poids moléculaire : 425.91
• Numéro MDL: MFCD00879135
• Code UNSPSC : 12352200
• ID de substance PubChem : 329770590
• Nomenclature NACRES : NA.77

Propriétés

• Pureté: ≥98% (HPLC)
• Forme: solid
• Conditions de stockage: desiccated
• Solubilité: DMSO: >10 mg/mL; H₂O: insoluble
• Auteur: Sanofi Aventis
• Chaîne SMILES: Cl.COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C3CCCO3
• InChI: 1S/C19H27N5O4.ClH/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19;/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23);1H
• Clé InChI: YTNKWDJILNVLGX-UHFFFAOYSA-N
• Informations sur le gène: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

Description

Actions biochimiques/physiologiques

Alfuzosin hydrochloride is an alpha-adrenergic blocker used to treat benign prostatic hyperplasia (BPH). It works by relaxing the muscles in the prostate and bladder neck, making it easier to urinate.

Caractéristiques et avantages

This compound is featured on the α1-Adrenoceptors and α2-Adrenoceptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves