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88930

Sigma-Aldrich

Thionin acetate salt

for microscopy (Bact., Bot., Hist.)

Synonyme(s) :

3,7-Diamino-5-phenothiazinium acetate, Lauth’s violet

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About This Item

Formule empirique (notation de Hill):
C12H9N3S · C2H4O2
Numéro CAS:
78338-22-4
Poids moléculaire :
287.34
Numéro C.I. (Colour Index):
52000
Numéro Beilstein :
4345073
Numéro MDL:
MFCD00081194
Code UNSPSC :
12352200
ID de substance PubChem :
57653323
Nomenclature NACRES :
NA.25

Qualité

for microscopy (Bact., Bot., Hist.)

Forme

powder

Technique(s)

titration: suitable

Chaîne SMILES 

CC([O-])=O.Nc1ccc2nc3ccc(N)cc3[s+]c2c1

InChI

1S/C12H10N3S.C2H4O2/c13-7-1-3-9-11(5-7)16-12-6-8(14)2-4-10(12)15-9;1-2(3)4/h1-6H,13-14H2;1H3,(H,3,4)/q+1;/p-1

Clé InChI

OWXBIRAFHWASMS-UHFFFAOYSA-M

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Application

Thionine (Lauth′s violet), a metachromatic dye, is widely used as a biological stain of materials such as DNA. Thionine is being studied as an electron mediator in the development of microbial fuel cells and electrochemical biosensors.

Code de la classe de stockage

13 - Non Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Liu Deng et al.
Analytical chemistry, 82(10), 4283-4287 (2010-04-21)
In this work we developed a fully integrated biofuel cell on a microchip, which consisted of glucose dehydrogenase supported (carbon nanotubes/thionine/gold nanoparticles)(8) multilayer as the anode, and the (carbon nanotubes/polylysine/laccase)(15) multilayer as the cathode. The as-obtained biofuel cell produced open
Ling Meng et al.
Biosensors & bioelectronics, 24(6), 1751-1756 (2008-10-24)
A glutamate biosensor based on the electrocatalytic oxidation of reduced nicotinamide adenine dinucleotide (NADH), which was generated by the enzymatic reaction, was developed via employing a single-walled carbon nanotubes/thionine (Th-SWNTs) nanocomposite as a mediator and an enzyme immobilization matrix. The
Yanyan Cai et al.
Biosensors & bioelectronics, 36(1), 6-11 (2012-05-09)
Interests in using nanoporous metals for biosensing applications have been increasing. Herein, nanotubular mesoporous PdCu (NM-PdCu) alloy is used to fabricate a novel label-free electrochemical immunosensor for cancer biomarker carcinoembryonic antigen (CEA). It operates through physisorption of anti-CEA on NM-PdCu
Limei Zhu et al.
Biosensors & bioelectronics, 35(1), 507-511 (2012-04-10)
A novel protocol for development of DNA electrochemical biosensor based on thionine-graphene nanocomposite modified gold electrode was presented. The thionine-graphene nanocomposite layer with highly conductive property was characterized by scanning electron microscopy, transmission electron microscopy, cyclic voltammetry and electrochemical impedance
Selvaraj Baskar et al.
Biosensors & bioelectronics, 33(1), 95-99 (2012-01-24)
We report here a novel detection scheme for simultaneous detection of NADH and H(2)O(2) based on a bifunctional poly(thionine)-modified electrode. Electropolymerization of thionine on a "preanodized" screen-printed carbon electrode effectively lowers the oxidation potential of NADH to 0.15 V (vs.
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