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Sigma-Aldrich

6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride

suitable for chemiluminescence, ≥98.0% (HPLC)

Synonyme(s) :

2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride, Cypridina Luciferin methoxy-analogue, MCLA

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About This Item

Formule empirique (notation de Hill):
C14H13N3O2 · HCl
Numéro CAS:
Poids moléculaire :
291.73
Numéro Beilstein :
5838857
Numéro MDL:
Code UNSPSC :
12352200
ID de substance PubChem :
Nomenclature NACRES :
NA.32

Description

luminescence test: Emmax465 nm, 0.1 M Tris pH 8.5; after addition of H2O2 (Chemiluminescence: in 0.1 M Tris pH 8.5; after addition of H2O2)

Pureté

≥98.0% (HPLC)

Forme

powder

Solubilité

DMSO: soluble
H2O: soluble

Adéquation

suitable for chemiluminescence

Chaîne SMILES 

Cl[H].COc1ccc(cc1)C2=CN3C(=O)C(C)=NC3=CN2

InChI

1S/C14H13N3O2.ClH/c1-9-14(18)17-8-12(15-7-13(17)16-9)10-3-5-11(19-2)6-4-10;/h3-8,15H,1-2H3;1H

Clé InChI

KGMPQNFFCUDXSO-UHFFFAOYSA-N

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Autres remarques

Generation of chemiluminescence by reaction with super oxide O2 or singlet oxygen. Used in research of leucocyte function.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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S Koga et al.
Archives of biochemistry and biophysics, 289(2), 223-229 (1991-09-01)
Heme compound, hematin or cytochrome c, catalyzes the decomposition of 13-hydroperoxy linoleic acid yielding both O2- and 1O2 under aerobic conditions. No 1O2 is produced when hydrogen peroxide and cumene hydroperoxide are used as substrates. In these experiments, both O2-
Keiko Suzuki et al.
Antioxidants (Basel, Switzerland), 9(6) (2020-06-13)
Bisphosphonates (BPs) are classified into two groups, according to their side chain structures, as nitrogen-containing BPs (NBPs) and non-nitrogen-containing BPs (non-NBPs). In this study, we examined the effects of NBPs and non-NBPs on inflammatory responses, by quantifying the inflammatory mediators
Julia M Diaz et al.
Nature communications, 7, 13801-13801 (2016-12-08)
The reactive oxygen species superoxide (O2·-) is both beneficial and detrimental to life. Within corals, superoxide may contribute to pathogen resistance but also bleaching, the loss of essential algal symbionts. Yet, the role of superoxide in coral health and physiology
Lucas J Beversdorf et al.
Water research, 140, 280-290 (2018-05-08)
Freshwater cyanobacterial blooms are becoming increasingly problematic in regions that rely on surface waters for drinking water production. Microcystins (MCs) are toxic peptides produced by multiple cyanobacterial genera with a global occurrence. Cyanobacteria also produce a variety of other toxic
Hagop Kojanian et al.
American journal of therapeutics, 23(6), e1456-e1463 (2014-05-08)
Statins have favorable effects on endothelial function partly because of their capacity to reduce oxidative stress. However, antioxidant vitamins, unlike statins, are not as cardioprotective, and this paradox has been explained by failure of vitamin antioxidants to ameliorate endoplasmic reticulum

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