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Y0001183

Diethanolamine

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Diethanolamine, 2,2′-Iminodiethanol, Bis(2-hydroxyethyl)amine

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About This Item

Formule linéaire :
HN(CH2CH2OH)2
Numéro CAS:
111-42-2
Poids moléculaire :
105.14
Numéro Beilstein :
605315
Numéro MDL:
MFCD00002843
Code UNSPSC :
41116107
ID de substance PubChem :
329831296
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Densité de vapeur

3.6 (vs air)

Pression de vapeur

<0.98 atm ( 100 °C)

Famille d'API

trolamine

Température d'inflammation spontanée

689 °F

Limite d'explosivité

10.6 %

Fabricant/nom de marque

EDQM

Indice de réfraction

n20/D 1.477 (lit.)

Point d'ébullition

217 °C/150 mmHg (lit.)

Pf

28 °C (lit.)

Densité

1.097 g/mL at 25 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

OCCNCCO

InChI

1S/C4H11NO2/c6-3-1-5-2-4-7/h5-7H,1-4H2

Clé InChI

ZBCBWPMODOFKDW-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Trolamine impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Health hazardCorrosionExclamation mark
GHS08,GHS05,GHS07

Mention d'avertissement

Danger

Mentions de danger

H302,H315,H318,H361fd,H373

Classification des risques

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 Oral

Organes cibles

Kidney,Liver,Blood

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

280.4 °F - closed cup

Point d'éclair (°C)

138 °C - closed cup

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Certificats d'analyse (COA)

Lot/Batch Number

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Honghui Yu et al.
Journal of immunology (Baltimore, Md. : 1950), 193(6), 2902-2910 (2014-08-15)
Anti-D can prevent immunization to the RhD Ag on RBCs, a phenomenon commonly termed Ab-mediated immune suppression (AMIS). The most accepted theory to explain this effect has been the rapid clearance of RBCs. In mouse models using SRBC, these xenogeneic
Hon-Wing Leung et al.
Regulatory toxicology and pharmacology : RTP, 43(3), 260-271 (2005-09-29)
Diethanolamine (DEA) is a chemical used widely in a number of industries and is present in many consumer products. Studies by the National Toxicology Program (NTP) have indicated that lifetime dermal exposure to DEA increased the incidence and multiplicity of
Choline deficiency associated with diethanolamine carcinogenicity.
Paul M Newberne
Toxicological sciences : an official journal of the Society of Toxicology, 67(1), 1-3 (2002-04-19)
Hae-Rim Kim et al.
PloS one, 10(4), e0124909-e0124909 (2015-04-22)
Vascular endothelial growth factor (VEGF) has angiogenic, inflammatory, and bone-destructive roles in rheumatoid arthritis (RA). We aimed to determine the unique role of VEGF in osteoclastogenesis in RA. VEGF-induced receptor activator of nuclear factor ҡB ligand (RANKL) expression was determined
M-L Metzger et al.
Clinical and experimental immunology, 179(2), 256-264 (2014-09-25)
Common variable immunodeficiency (CVID) encompasses a heterogeneous group of antibody deficiencies characterized by susceptibility to recurrent infections and sequelae, including bronchiectasis. We investigated the relevance of the lectin complement pathway in CVID patients by analysing ficolin-2 and ficolin-3 serum levels
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