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Y0000441

Didanosine impurity A,

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Hypoxanthine, 6-Hydroxypurine

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About This Item

Formule empirique (notation de Hill):
C5H4N4O
Numéro CAS:
Poids moléculaire :
136.11
Numéro Beilstein :
5811
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

didanosine

Fabricant/nom de marque

EDQM

Pf

>300 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

O=C1NC=Nc2nc[nH]c12

InChI

1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)

Clé InChI

FDGQSTZJBFJUBT-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hypoxanthine is a nutrient additive for a variety of cell culture applications involving bacterial, parasite (Plasmodium falciparum) and animal cells. Hypoxanthine is a component of selection media used in hybridoma technologies.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Matthias M Heck et al.
European urology, 66(2), 222-229 (2013-03-08)
To determine the anatomic extent of pelvic lymph node dissection (PLND) in prostate cancer (PCa) patients at the time of radical prostatectomy (RP), knowledge about the topography of lymph node (LN) metastases is required. Because small-volume LN metastases may be
Chia-Tung Wu et al.
Cardiovascular research, 102(3), 487-496 (2014-03-07)
Fibroblasts, which play an important role in cardiac function/dysfunction, including arrhythmogenesis, have voltage-dependent (Kv) currents of unknown importance. Here, we assessed the differential expression of Kv currents between atrial and ventricular fibroblasts from control dogs and dogs with an atrial
Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production.
O D Saugstad
Pediatric research, 23(2), 143-150 (1988-02-01)
Katie May Slattery et al.
Medicine and science in sports and exercise, 46(6), 1114-1123 (2014-03-01)
This investigation examined the ergogenic effect of short-term oral N-acetylcysteine (NAC) supplementation and the associated changes in redox balance and inflammation during intense training. A double-blind randomized placebo-controlled crossover design was used to assess 9 d of oral NAC supplementation
Derek B J Bone et al.
Microvascular research, 95, 68-75 (2014-07-01)
Purine nucleosides and nucleobases play key roles in the physiological response to vascular ischemia/reperfusion events. The intra- and extracellular concentrations of these compounds are controlled, in part, by equilibrative nucleoside transporter subtype 1 (ENT1; SLC29A1) and by equilibrative nucleobase transporter

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