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Y0000352

Beclometasone dipropionate for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Beclomethasone dipropionate, 9-Chloro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate

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About This Item

Formule empirique (notation de Hill):
C28H37ClO7
Numéro CAS:
5534-09-8
Poids moléculaire :
521.04
Numéro MDL:
MFCD00135613
Code UNSPSC :
41116107
ID de substance PubChem :
329830914
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

beclometasone

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C

InChI

1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1

Clé InChI

KUVIULQEHSCUHY-XYWKZLDCSA-N

Informations sur le gène

human ... NR3C1(2908)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Beclometasone dipropionate for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1048506

Beclomethasone dipropionate, United States Pharmacopeia (USP) Reference Standard

B0305000

Beclomethasone dipropionate, anhydrous, European Pharmacopoeia (EP) Reference Standard

Y0000351

Beclometasone dipropionate monohydrate, European Pharmacopoeia (EP) Reference Standard

Y0000469

Beclometasone dipropionate for peak identification, European Pharmacopoeia (EP) Reference Standard

Y0001073

Beclometasone dipropionate impurities F and N, European Pharmacopoeia (EP) Reference Standard

BP030

Beclometasone (beclomethasone) dipropionate, British Pharmacopoeia (BP) Assay Standard

PHR1619

Beclomethasone Dipropionate, Pharmaceutical Secondary Standard; Certified Reference Material

1048517

Beclomethasone Dipropionate Related Compound A, United States Pharmacopeia (USP) Reference Standard

1048543

Beclomethasone Dipropionate Related Compound H, United States Pharmacopeia (USP) Reference Standard

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Warning

Mentions de danger

H361fd,H373

Classification des risques

Repr. 2 - STOT RE 2

Organes cibles

Adrenal gland,Immune system,Bone

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

P Chervinsky
Clinical therapeutics, 18(5), 790-796 (1996-09-01)
A new double-strength (84 micrograms/spray) formulation of beclomethasone dipropionate (BDP-ds) as an aqueous suspension has been introduced to control symptoms of allergic rhinitis with once-daily intranasal dosing. This paper reviews the results of three clinical reports which show that BDP-ds
S E Libretto
Archives of toxicology, 69(8), 509-525 (1995-01-01)
This paper reviews the published toxicity of beclomethasone dipropionate (BDP). BDP is a synthetic glucocorticosteroid which has a powerful local anti-inflammatory effect but little systemic action. It has been developed for both dermatological and inhaled applications. LD50 values and other
B Davies
The British journal of clinical practice, 47(2), 87-93 (1993-03-01)
Several reports have claimed that beclomethasone dipropionate (BDP) and budesonide (BUD) differ with regard to therapeutic efficacy and associated adverse effects, based either upon clinical data, or upon theoretical considerations. Although long-term comparisons are lacking, the consensus of numerous studies
R N Brogden et al.
Drugs, 28(2), 99-126 (1984-08-01)
Inhaled beclomethasone dipropionate is now well established in the management of asthma. Studies conducted over the last decade, and since the drug was previously reviewed in the Journal, have confirmed that inhaled beclomethasone dipropionate 400 to 800 micrograms daily can
A R Boobis
Respiratory medicine, 92 Suppl B, 2-6 (1999-04-08)
The physicochemical and pharmacokinetic characteristics of BDP and budesonide are somewhat different, but the overall result is that both are well suited for use as inhaled corticosteroids. Both BDP and budesonide are metabolized primarily by the liver, with one of
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