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Y0000196

Ondansetron for TLC system suitability

Name: Ondansetron for TLC system suitability
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Ondansetron hydrochloride dihydrate, 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride, GR 38032F

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About This Item

Formule empirique (notation de Hill):

C₁₈H₁₉N₃O · HCl · 2H₂O

Numéro CAS:

103639-04-9

Poids moléculaire :

365.85

Numéro MDL:

MFCD00374371

Code UNSPSC :

41116107

ID de substance PubChem :

329830878

Nomenclature NACRES :

NA.24

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Ondansetron impurity F

Y0000218

Ondansetron hydrochloride dihydrate

Supelco

70221

Formate d′ammonium

Y0001326

Imidazole

Sigma-Aldrich

SMB00937

Fatty Acid Methyl Esters Standard Mixture

Supelco

18919-1AMP

F.A.M.E. Mélange, C4-C24

Sigma-Aldrich

779423

Ammoniac solution

Qualité

pharmaceutical primary standard

Famille d'API

ondansetron

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES

Cl[H].[H]O[H].[H]O[H].Cc1nccn1CC2CCc3c(C2=O)c4ccccc4n3C

InChI

1S/C18H19N3O.ClH.2H2O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2;;;/h3-6,9-10,13H,7-8,11H2,1-2H3;1H;2*1H2

Clé InChI

VRSLTNZJOUZKLX-UHFFFAOYSA-N

Informations sur le gène

human ... HTR3A(3359)

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Catégories apparentées

Étalons de référence analytiques | Sigma-Aldrich

Étalons des instituts de métrologie et des pharmacopées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ondansetron for TLC system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

5-HT₃serotonin receptor antagonist

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit

Description

Tarif

PHR1141

Ondansetron Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

1478618

1478593

1478629

PHR2224

PHR2223

PHR2221

Pictogrammes

GHS06,GHS05,GHS09

Mention d'avertissement

Danger

Mentions de danger

H301,H318,H410

Conseils de prudence

P264 - P273 - P280 - P301 + P310 - P305 + P351 + P338 - P391

Classification des risques

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Do children with high body mass indices have a higher incidence of emesis when undergoing ketamine sedation?

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Pediatric emergency care, 28(11), 1203-1205 (2012-11-02)

The objective of this study was to determine if overweight children are more likely than normal-weight children to require ondansetron when undergoing ketamine sedation in a pediatric emergency department. Patients between the ages of 2 and 18 years with an

Ondansetrone or metoclopromide? Which is more effective in severe nausea and vomiting of pregnancy? A randomized trial double-blind study.

Mehrdad Kashifard et al.

Clinical and experimental obstetrics & gynecology, 40(1), 127-130 (2013-06-04)

Nausea and vomiting of pregnancy (NVP) are seen in 50-80% of pregnancies. However, in severe NVP, called hypermesis gravidarum (HG), medical therapy to reduce nausea and vomiting is inevitable and ondansetron (OND) as an effective drug has recently been proposed.

Thiolated xyloglucan: Synthesis, characterization and evaluation as mucoadhesive in situ gelling agent.

Hitendra S Mahajan et al.

Carbohydrate polymers, 91(2), 618-625 (2012-11-06)

The objective of present study was to enhance bioadhesive potential of xyloglucan by thiolation. Thiolation of xyloglucan was achieved with esterification with thioglycolic acid. Thiolated xyloglucan was characterized by NMR, DSC, and XRD analysis. Thiolated xyloglucan was determined to possess

A pilot study of full-dose ondansetron to treat heavy-drinking men withdrawing from alcohol in Brazil.

João Maria Corrêa Filho et al.

Addictive behaviors, 38(4), 2044-2051 (2013-02-12)

Ondansetron has emerged as a promising medication for the treatment of alcohol dependence, mainly among early-onset alcoholics. This research primarily aimed to evaluate the efficacy and safety of ondansetron at a 16mg/day dosage to treat alcohol-dependent outpatients. A double-blind, placebo-controlled

Development of HPTLC method for the estimation of ondansetron hydrochloride in bulk drug and sublingual tablets.

Ali Mujtaba et al.

Drug testing and analysis, 5(2), 122-125 (2013-02-16)

A new, simple, rapid, accurate and precise high performance thin layer chromatography (HPTLC) method has been developed for the estimation of ondansetron hydrochloride in bulk and sublingual tablets. The mobile phase composition was chloroform : ethyl acetate : methanol :

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