Y0000155

Tramadol hydrochloride

European Pharmacopoeia (EP) Reference Standard

• Synonyme(s) : (±)-cis-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride
• Formule empirique (notation de Hill): C₁₆H₂₅NO₂ · HCl
• Numéro CAS: 36282-47-0
• Poids moléculaire : 299.84
• Numéro MDL: MFCD00798507
• Code UNSPSC : 41116107
• ID de substance PubChem : 329830868
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: tramadol
• Fabricant/nom de marque: EDQM
• Contrôle du médicament: USDEA Schedule IV
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: Cl.COc1cccc(c1)[C@@]2(O)CCCC[C@@H]2CN(C)C
• InChI: 1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1
• Clé InChI: PPKXEPBICJTCRU-XMZRARIVSA-N

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Tramadol is a synthetic opiate agonist analgesic, widely used in patients suffering from moderate to severe chronic pain. It is considered safe when compared to other opioids. It contributes to the analgesic activity by blocking the nociceptive impulses at the spinal level, inhibiting the norepinephrine and serotonin reuptake.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Opioid analgesic; P450 substrate.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H301,H336,H411
• Conseils de prudence: P261 - P264 - P271 - P273 - P301 + P310 - P304 + P340 + P312
• Classification des risques: Acute Tox. 3 Oral - Aquatic Chronic 2 - STOT SE 3
• Organes cibles: Central nervous system
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable