PHR1332
L-Proline
Pharmaceutical Secondary Standard; Certified Reference Material
Synonyme(s) :
Acide (S)-pyrrolidine-2-carboxylique
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About This Item
Formule empirique (notation de Hill):
C5H9NO2
Numéro CAS:
Poids moléculaire :
115.13
Numéro Beilstein :
80810
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24
Produits recommandés
Qualité
certified reference material
pharmaceutical secondary standard
Niveau de qualité
Agence
traceable to Ph. Eur. P3350000
traceable to USP 1568506
Famille d'API
proline
CofA (certificat d'analyse)
current certificate can be downloaded
Technique(s)
HPLC: suitable
gas chromatography (GC): suitable
Pf
228 °C (dec.) (lit.)
Application(s)
pharmaceutical (small molecule)
Format
neat
Température de stockage
2-30°C
Chaîne SMILES
OC(=O)[C@@H]1CCCN1
InChI
1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
Clé InChI
ONIBWKKTOPOVIA-BYPYZUCNSA-N
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Description générale
L-Proline is a non-essential amino acid. Peptides bond to proline, making it a useful building block for proteins. It can be used as a cell culture media component for the commercial biomanufacturing of therapeutic recombinant proteins and monoclonal antibodies.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
L-Proline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Remarque sur l'analyse
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Autres remarques
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Note de bas de page
To see an example of a Certificate of Analysis for this material enter LRAC3756 in the slot below. This is an example certificate only and may not be the lot that you receive.
Produits recommandés
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Code de la classe de stockage
13 - Non Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Les clients ont également consulté
Proline
USP42-NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 3683-3683 (2018)
Daniel R Knight et al.
Applied and environmental microbiology, 81(1), 119-123 (2014-10-19)
Clostridium difficile is an important enteric pathogen of humans and the cause of diarrhea and enteritis in neonatal pigs. Outside Australia, prevalence in piglets can be up to 73%, with a single PCR ribotype (RT), 078, predominating. We investigated the
John M Curto et al.
Organic letters, 16(7), 1948-1951 (2014-03-29)
The first asymmetric synthesis of α-allyl-α-aryl α-amino acids by means of a three-component coupling of α-iminoesters, Grignard reagents, and cinnamyl acetate is reported. Notably, the enolate from the tandem process provides a much higher level of reactivity and selectivity than
Marco Scocchi et al.
Cellular and molecular life sciences : CMLS, 68(13), 2317-2330 (2011-05-20)
Proline-rich antimicrobial peptides are a group of cationic host defense peptides of vertebrates and invertebrates characterized by a high content of proline residues, often associated with arginine residues in repeated motifs. Those isolated from some mammalian and insect species, although
Frederic Bringaud et al.
Frontiers in bioscience (Landmark edition), 17, 349-374 (2011-12-29)
Trypanosomatids are a large family of unicellular eukaryotes, many of which are parasites in higher eukaryotes including man. Much of our understanding of metabolism in these organisms has been gained form the study of the human infective representatives (Trypanosoma brucei
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