C1900000

Chlorpromazine hydrochloride

European Pharmacopoeia (EP) Reference Standard

• Synonyme(s) : Largactil
• Formule empirique (notation de Hill) : C₁₇H₁₉ClN₂S · HCl
• Numéro CAS: 69-09-0
• Poids moléculaire : 355.33
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329774913
• MDL number: MFCD00012654
• Beilstein/REAXYS Number: 3779989

Propriétés

• grade: pharmaceutical primary standard
• API family: chlorpromazine
• manufacturer/tradename: EDQM
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13
• InChI: 1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H
• InChI key: FBSMERQALIEGJT-UHFFFAOYSA-N
• Gene Information: human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of hemoglobin and peroxidase.

Biochem/physiol Actions

La chlorpromazine manifeste une activité cytotoxique et antiproliférative contre les cellules leucémiques mais elle ne modifie pas la viabilité des lymphocytes normaux.

Phénothiazine antipsychotique ; antagoniste du récepteur D₂ de la dopamine, antagoniste du récepteur H₁ de l′histamine ; inhibe la stimulation calmoduline-dépendante de la nucléotide cyclique phosphodiestérase et de l′oxyde nitrique synthase.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Informations sur la sécurité

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H330
• pcodes: P260 - P264 - P270 - P271 - P284 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 3 Oral
• Classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable