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B7536

Supelco

Buprenorphine hydrochloride solution

analytical standard, for drug analysis

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About This Item

Formule empirique (notation de Hill):
C29H41NO4 · HCl
Numéro CAS:
Poids moléculaire :
504.10
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

analytical standard, for drug analysis

Niveau de qualité

drug control

Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

pharmaceutical (small molecule)

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES 

Cl.CO[C@]12CC[C@@]3(CC1[C@](C)(O)C(C)(C)C)[C@H]4Cc5ccc(O)c6OC2[C@]3(CCN4CC7CC7)c56

InChI

1S/C29H41NO4.ClH/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28;/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3;1H/t20-,21-,24-,26+,27-,28+,29-;/m1./s1

Clé InChI

UAIXRPCCYXNJMQ-RZIPZOSSSA-N

Application

Buprenorphine hydrochloride solution may be used as a reference standard in the determination of buprenorphine in samples of human plasma using gas chromatography coupled with mass spectrometry (GC/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogrammes

FlameSkull and crossbonesHealth hazard

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

51.8 °F - closed cup

Point d'éclair (°C)

11 °C - closed cup

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves


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Certificats d'analyse (COA)

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Bilin Liu et al.
STAR protocols, 1(3), 100186-100186 (2020-12-31)
Here, we present a modified protocol for a mouse heart failure (HF) model using minimally invasive transverse aortic constriction (miTAC). miTAC is a more effective method in mice than the standard open-chest transverse aortic constriction (TAC) to generate an HF
Development and validation of a sensitive analytical method for the simultaneous determination of buprenorphine and norbuprenorphine in human plasma.
Gopal S, et al.
European Journal of Pharmaceutics and Biopharmaceutics, 51(2), 147-151 (2001)
Afarin Rahimi-Movaghar et al.
The Cochrane database of systematic reviews, 1(1), CD007775-CD007775 (2013-02-27)
Pharmacologic therapies for maintenance treatment of heroin dependence have been used and studied widely. Systematic reviews have demonstrated the effectiveness of such therapies. Opium dependence is associated with less problems and impairments and is less likely to be used by
Robert P Schwartz et al.
American journal of public health, 103(5), 917-922 (2013-03-16)
We examined the association between the expansion of methadone and buprenorphine treatment and the prevalence of heroin overdose deaths in Baltimore, Maryland from 1995 to 2009. We conducted a longitudinal time series analysis of archival data using linear regression with
Vincent Laprevote et al.
Presse medicale (Paris, France : 1983), 42(7-8), 1085-1090 (2013-03-23)
Opioid maintenance treatments (OMT) reduce illicit opiate use and its associated risks. They are often prescribed on a long-term basis. Physiological changes induced by long-term OMT may cause hyperalgesia and cross-tolerance to opioid agonists, which suggests that the dosage of

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