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BSA + TMCS

for GC derivatization, LiChropur, 93.0-97.0% (GC)

Synonyme(s) :

Bis(trimethylsilyl)acetamide + Trimethylchlorosilane

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About This Item

Code UNSPSC :
41116105
ID de substance PubChem :
Nomenclature NACRES :
NA.22

Qualité

for GC derivatization
LiChropur

Niveau de qualité

Pureté

93.0-97.0% (GC)

Composition

trimethylchlorosilane (minor component), 3.0-5.0% GC

Pertinence de la réaction

reagent type: derivatization reagent
reaction type: Silylations

Technique(s)

gas chromatography (GC): suitable

Description générale

BSA+TMCS combination, is one of the most commonly used silylating reagents. BSA is readily used for silylating a wide range of functional groups such as non-sterically hindered alcohols, amides, amines, amino acids, carboxylic acids, and enols. TMCS is a silylation catalyst always used with other silylation reagents to increase the reactivity in derivatization of alcohols, alkaloids, amines, biogenic amines, carboxylic acids, phenols, and steroids.

Application

Learn more in the Product Information
Suitable for the derivatization of α-ketoacids, amines, amino acids, cycloserine, histamine and metabolites, phenylethylamines, phosphatidylserines and tryptamines. BSA+TMCS may be used as a derivatizing reagent for the determination of steryl glycosides in biodiesel using gas chromatography–mass spectrometry.
Suitable for the derivatization of a-ketoacids, amines, amino acids, cycloserine, histamine and metabolites, phenylethylamines, phosphatidylserines and tryptamines.

Caractéristiques et avantages

  • BSA+TMCS has good solvent properties and can function as a silylation reagent without additional solvents.        
  • Alternatively, the mixture is very soluble in most commonly used silylation solvents.        
  • This combination is extremely sensitive to moisture and should be handled under dry conditions.

Autres remarques

Mélange de silylation puissant avec large gamme d′applications
Reagent for trimethylsilyl diglyceride, trimethylsilyl (TMS) and trimethylsilyl oximes.

Informations légales

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

FlameCorrosionExclamation mark

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 4 Oral - Flam. Liq. 2 - Skin Corr. 1A

Risques supp

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

53.6 °F - closed cup

Point d'éclair (°C)

12 °C - closed cup

Équipement de protection individuelle

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Consulter la Bibliothèque de documents

Removal of pharmaceuticals during drinking water treatment.
Terness TA
Environmental Science & Technology, 36 (17), 3855-3863 (2002)
Victor Crivianu-Gaita et al.
Biosensors & bioelectronics, 78, 92-99 (2015-11-26)
There are currently no biosensors that are able to reliably detect the process of cancer metastasis. We describe the first label-free real-time ultra-high frequency acoustic wave biosensor prototype capable of detecting the breast and prostate cancer metastasis biomarker, parathyroid hormone-related
D.L. Sondack et al.
Journal of Pharmacological Sciences, 62, 1344-1344 (1973)
D.R. Knapp
Handbook of Analytical Derivatization Reactions, 202-202 (1979)
J. Heberle et al.
Silylating Agents, 2nd ed. (1995)

Articles

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

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