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Benzylamine

for GC derivatization, LiChropur™, ≥99.0%

Synonyme(s) :

α-Aminotoluène

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About This Item

Formule linéaire :
C6H5CH2NH2
Numéro CAS:
100-46-9
Poids moléculaire :
107.15
Numéro Beilstein :
741984
Numéro CE :
202-854-1
Numéro MDL:
MFCD00008106
Code UNSPSC :
12000000
eCl@ss :
39030404
ID de substance PubChem :
329750088
Nomenclature NACRES :
NA.22

Qualité

for GC derivatization
LiChropur™

Niveau de qualité

100

Pureté

≥99.0% (GC)
≥99.0%

Forme

liquid

Technique(s)

gas chromatography (GC): suitable

Indice de réfraction

n20/D 1.543 (lit.)
n20/D 1.543

Point d'ébullition

184-185 °C (lit.)

Pf

10 °C (lit.)

Solubilité

H2O: soluble

Densité

0.981 g/mL at 25 °C (lit.)

Chaîne SMILES 

NCc1ccccc1

InChI

1S/C7H9N/c8-6-7-4-2-1-3-5-7/h1-5H,6,8H2

Clé InChI

WGQKYBSKWIADBV-UHFFFAOYSA-N

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Description générale

Benzylamine, a primary amine, can be used as a fluorescence derivatization agent for the sensitive and selective determination of analytes by chromatography techniques coupled with fluorescence detection.

Application

Benzylamine may be used as a derivatization agent to increase the sensitivity of 5-hydroxyindoles, catecholamines and catechols in biological samples prior to their determination using high performance liquid chromatography (HPLC) coupled with fluorescence detection.

Produits recommandés

Discover LiChropur™ reagents ideal for HPLC or LC-MS analysis

Informations légales

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

CorrosionExclamation mark
GHS05,GHS07

Mention d'avertissement

Danger

Mentions de danger

H302 + H312,H314

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

149.0 °F - closed cup

Point d'éclair (°C)

65 °C - closed cup

Équipement de protection individuelle

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificats d'analyse (COA)

Lot/Batch Number
BCCM4389
BCCL4617
BCCK0792
BCCK6435
BCCH2116

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Simultaneous determination of norepinephrine, serotonin, and 5-hydroxyindole-3-acetic acid in microdialysis samples from rat brain by microbore column liquid chromatography with fluorescence detection following derivatization with benzylamine
Yoshitake T, et al.
Analytical Biochemistry, 312(2), 125-133 (2003)
The Derivatization of Proquinoidal Analytes with 1, 2-Diphenylethane-1, 2-Diamine (DPE) and Benzylamine (BA): An Investigation of Products, Yields, Kinetics and Reagent Selectivity
Woods JM, et al.
Chromatographia, 78(3-4), 163-178 (2015)
Kaoru Fujino et al.
Journal of chromatography. A, 1012(2), 169-177 (2003-10-03)
A highly selective and sensitive method for the simultaneous determination of 5-hydroxyindoles and catechols (serotonin, norepinephrine, dopamine and related compounds) by high-performance liquid chromatography with fluorescence detection is described. The method is based on the two-step precolumn derivatization of 5-hydroxyindoles
Danielle M Shacklady-McAtee et al.
Organic letters, 13(13), 3490-3493 (2011-06-08)
A nickel(0) catalyst effectively mediates the cyclization of N-benzoyl aminals in the presence of a stoichiometric Lewis acid. This method enables preparation of a variety of isoindolinones with substitution on the benzoyl fragment and C-3 carbon. This reaction likely proceeds
Fei Mao et al.
Bioorganic & medicinal chemistry, 20(19), 5884-5892 (2012-09-05)
In an effort to identify novel multifunctional drug candidates for the treatment of Alzheimer's disease (AD), a series of hybrid molecules were synthesised by reacting N-(aminoalkyl)tacrine with salicylic aldehyde or derivatives of 2-aminobenzaldehyde. These compounds were then evaluated as multifunctional
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