06369
Lipid binding constant determination kit
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About This Item
Code UNSPSC :
12352200
Nomenclature NACRES :
NA.25
Produits recommandés
Contient
0.0005% NaN3 as preservative
Concentration
30-35 mM lipid (Transil®-L pellet)
Superficie
~10 m2/g
Taille des particules
~30 μm
Dimension de pores
~4000 Å pore diameter
Température de stockage
2-8°C
Application
Lipid binding constant determination kit is used for analysis of lipid binding.
Composants
TRANSIL®-Ln (neutral biomembrane);
1 mL TRANSIL®-Lc (biomembrane with negative charge clusters); 1 ml
each in 5 mL buffer (20 mM HEPES pH 7.0; 0.03 M NaCl)
TRANSIL®-L consists of a silicate core; encased in a mobile lipid bilayer (phospholipids).
1 mL TRANSIL®-Lc (biomembrane with negative charge clusters); 1 ml
each in 5 mL buffer (20 mM HEPES pH 7.0; 0.03 M NaCl)
TRANSIL®-L consists of a silicate core; encased in a mobile lipid bilayer (phospholipids).
Informations légales
Transil is a registered trademark of Nimbus GmbH
Code de la classe de stockage
12 - Non Combustible Liquids
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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A Loidl-Stahlhofen et al.
Journal of pharmaceutical sciences, 90(5), 599-606 (2001-04-05)
Quantification of membrane affinity is an important early screening step in modern drug design. However, current approaches using different lipid membrane models usually are time-consuming or show severe experimental drawbacks. In this paper we describe the use of solid-supported lipid
A Loidl-Stahlhofen et al.
Pharmaceutical research, 18(12), 1782-1788 (2002-01-12)
Lipid-water partitioning of 187 pharmaceuticals has been assessed with solid-supported lipid membranes (TRANSIL) in microwell plates and with multilamellar liposomes for a data comparison. The high-throughput potential of the new approach was evaluated. Drugs were incubated at pH 7.4 with
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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