00170580

Ginsenoside Rb1

primary reference standard

• Synonyme(s) : 2-O-β-Glucopyranosyl-(3β,12β)-20-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl β-D-glucopyranoside, Arasaponin E1, Gynosaponin C, Gypenoside III, Notoginsenoside Rb1, Panaxoside Rb1, Sanchinoside E1, Sanchinoside Rb1
• Formule empirique (notation de Hill): C₅₄H₉₂O₂₃
• Numéro CAS: 41753-43-9
• Poids moléculaire : 1109.29
• Numéro CE : 255-532-8
• Numéro MDL: MFCD00133367
• Code UNSPSC : 85151701
• ID de substance PubChem : 329747011
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: primary reference standard
• Durée de conservation: limited shelf life, expiry date on the label
• Fabricant/nom de marque: HWI
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Chaîne SMILES: C\C(C)=C\CC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]3CC[C@]4(C)[C@@H]3[C@H](O)C[C@@H]5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(C)(C)[C@@H]6CC[C@@]45C
• InChI: 1S/C54H92O23/c1-23(2)10-9-14-54(8,77-48-44(69)40(65)37(62)29(74-48)22-70-46-42(67)38(63)34(59)26(19-55)71-46)24-11-16-53(7)33(24)25(58)18-31-51(5)15-13-32(50(3,4)30(51)12-17-52(31,53)6)75-49-45(41(66)36(61)28(21-57)73-49)76-47-43(68)39(64)35(60)27(20-56)72-47/h10,24-49,55-69H,9,11-22H2,1-8H3/t24-,25+,26+,27+,28+,29+,30-,31+,32-,33-,34+,35+,36+,37+,38-,39-,40-,41-,42+,43+,44+,45+,46+,47-,48-,49-,51-,52+,53+,54-/m0/s1
• Clé InChI: GZYPWOGIYAIIPV-JBDTYSNRSA-N

Description

Description générale

Produced and qualified by HWI pharma services GmbH.
Exact content measured by quantitative NMR can be found on the certificate.

Ginsenoside Rb₁ is one of the primary constituents of traditional Chinese medicine, Ginseng. It belongs to the group of triterpene saponins called ginsenosides and pharmacologically, it is one of the most active dammarane-type ginsenosides. It is known to have anti-tumor, anti-oxidant, anti-inflammatory, and cytoprotective properties.

Application

The primary reference standard can be used for identification, assay, and purity testing, method development, and validation.It can also be used as follows:

• Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of ginsenoside Rb₁, naringin, ginsenoside Rb₂, and oridonin in rat plasma samples after administrating them weifuchun tablets
• Multi-residue analysis of baicalin, baicalein, wogonoside, wogonin, scutellarin, berberine, coptisine, ginsenoside Rb₁, and ginsenoside Re in biological samples of rat plasma by liquid chromatographic-tandem mass spectrometric (LC/MS/MS) method
• Analysis of traditional Chinese herbal decoctions of Dushen Tang and Shenfu Tang for the quantification of 12 ginsenosides by UPLC-MS/MS technique
• Analysis of rhizomes and roots of ginseng for the detection of 131 ginsenosides by UHPLC combined with a diode-array detector and quadrupole/time of flight tandem mass spectrometry (DAD-QTOF-MS/MS), along with the further determination of 19 ginsenosides by HPLC coupled with electrospray ionization-mass spectrometric detection

Autres remarques

This compound is commonly found in plants of the genus: panax

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Conseils de prudence: P264 - P270 - P301 + P312 - P501
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable