Accéder au contenu
Merck
Toutes les photos(1)

Documents

PC150

Sigma-Aldrich

Anti-β-Amyloid (1-42) Rabbit pAb

liquid, Calbiochem®

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme


About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

liquid

Ne contient pas

preservative

Espèces réactives

human

Conditionnement

antibody small pack of 25 μg

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze
avoid repeated freeze/thaw cycles

Isotype

IgG

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... APP(351)

Description générale

Rabbit polyclonal antibody adsorbed against Aβ1-40 and Aβ1-43, followed by immunoaffinity purification. Recognizes specifically β-amyloid peptide (1-42).
Recognizes specifically β-amyloid peptide (1-42). Does not cross-react with β-amyloid peptide (1-40) or β-amyloid peptide (1-43).
  • Antibody Target Gene Symbol: APP
  • Target Synonym: AAA, AD1, Adap, AL024401, Amyloid precursor, Amyloidogenic glycoprotein, APP isoform 1, APPI, appican, CTFgamma, CVAP, E030013M08RIK, Nexin II, P3, PN2, PreA4, PROTEASE NEXIN2
  • Entrez Gene Name: amyloid beta (A4) precursor protein
  • Hu Entrez ID: 351 (Related Antibodies: 171610, PC729,PC152, PC151, PC149, NE1012,171609, 171608, 171607, 171606, 171605, 171604, 171603, 171598, 171537)
  • Mu Entrez ID: 11820
  • Rat Entrez ID: 54226
  • This Anti-β-Amyloid (1-42) Rabbit pAb is validated for use in Dot Blot, ELISA, Radioimmunoassay for the detection of β-Amyloid (1-42).

    Immunogène

    Human
    a synthetic peptide corresponding to amino acids from a C-terminal fragment of human β-amyloid peptide (1-42)

    Application

    Dot Blot (0.1-0.5 µg/ml)

    ELISA (0.1-0.5 µg/ml)

    Radioimmunoassay (0.5 µg/ml)

    Conditionnement

    Please refer to vial label for lot-specific concentration.

    Avertissement

    Toxicity: Standard Handling (A)

    Forme physique

    In phosphate buffer, pH 7.4.

    Reconstitution

    Following initial thaw, aliquot and freeze (-20°C).

    Autres remarques

    Savage, M.J., et al. 1998. J. Neurosci.15, 1743.
    Borchelt, D.R., et al. 1997. Neuron19, 939.
    Citron, M., et al. 1997. Nature Med.3, 67.
    Hardy, J. 1997. Trends in Neurosci.20, 154.
    Solomon, B., et al. 1997. Proc. Natl. Acad. Sci. USA94, 4109.
    Duff, K., et al. 1996. Nature383, 710.
    Iwatsubo, T., et al. 1994. Neuron13, 45.
    Suzuki, N., et al. 1994. Science264, 133.
    This antibody is specific for β-amyloid peptide [1-42] and shows no reactivity to β-amyloid peptide [1-40] or β-amyloid peptide [1-43]. This antibody is recommended for use in the quantitative determination of β-amyloid peptide [1-42]. The sensitivity level for sandwich ELISA is 15-25 pg. Antibody should be titrated for optimal results in individual systems.

    Informations légales

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

    Not finding the right product?  

    Try our Outil de sélection de produits.

    Code de la classe de stockage

    10 - Combustible liquids

    Classe de danger pour l'eau (WGK)

    WGK 1

    Point d'éclair (°F)

    Not applicable

    Point d'éclair (°C)

    Not applicable


    Certificats d'analyse (COA)

    Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

    Déjà en possession de ce produit ?

    Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

    Consulter la Bibliothèque de documents

    Rebekkah W Halford et al.
    Proceedings of the National Academy of Sciences of the United States of America, 106(9), 3502-3506 (2009-02-11)
    Alterations in cellular cholesterol synthesis or content in cultured neurons affect the cleavage of amyloid precursor protein to amyloidogenic Abeta(40) and Abeta(42) peptides characteristic of Alzheimer's disease. To determine whether a decrease in cholesterol synthesis affects amyloid precursor protein processing
    Hisham Qosa et al.
    The Journal of nutritional biochemistry, 26(12), 1479-1490 (2015-09-08)
    Extra-virgin olive oil (EVOO) is one of the main elements of Mediterranean diet. Several studies have suggested that EVOO has several health promoting effects that could protect from and decrease the risk of Alzheimer's disease (AD). In this study, we
    Hisham Qosa et al.
    ACS chemical neuroscience, 6(11), 1849-1859 (2015-09-09)
    Numerous clinical and preclinical studies have suggested several health promoting effects for the dietary consumption of extra-virgin olive oil (EVOO) that could protect and decrease the risk of developing Alzheimer's disease (AD). Moreover, recent studies have linked this protective effect

    Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

    Contacter notre Service technique