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Sigma-Aldrich

Heart dECM Gel Hydrogel Kit

Synonyme(s) :

Heart dECM Gel Hydrogel Kit

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About This Item

Code UNSPSC :
12352207
Nomenclature NACRES :
NA.81

Source biologique

Porcine

Conditionnement

pkg of 1 kit

Fabricant/nom de marque

Sigma-Aldrich

Mode de croissance

N/A

Technique(s)

cell culture | mammalian: suitable

Conditions d'expédition

ambient

Température de stockage

2-8°C

Description générale

The cellular microenvironment directly and indirectly effects cellular behavior via both biophysical and biochemical routes. The microenvironment is composed of extracellular matrix proteins (ECM), other surrounding cells, cytokines, growth factors, hormones, and other bioactive agents and nano/microscale mechanical properties such as physical tension/stiffness. Decellularization is the process used in biomedical engineering to isolate the native extracellular matrix (ECM) of a tissue from its inhabiting cells, leaving an ECM scaffold of the original tissue, which can be used in cell culture and tissue regeneration. Compared to other tumor derived basement membrane extracts (Matrigel@), these dECM hydrogel scaffolds can provide a more physiological environment with increased growth rates for cells without the use of any exogenous growth factors. Our tissue-specific dECM Gel Hydrogel Kits are a series of native decellularized extracellular matrix (ECM) protein solutions derived from a variety of non-diseased porcine organs (bone, heart, liver, kidney, intestine, skin and lung). These hydrogels can be used as traditional 2D ECM coatings or as hydrogels to encapsulate cells for 3D cell culture applications.

Application

pH: 2.0-3.0Gelation: Forms GelBiocompatibility: 90% Cell ViabilitySterility: No Fungi or Bacteria DetectedMycoplasma: NegativePRRS, PRV: Negative

Caractéristiques et avantages

Heart decellularized ECM scaffold for traditional 2D and 3D cell culture applications.

Stockage et stabilité

Store all components of the dECM Gel Hydrogel Kit at 2-8°C (do not freeze).

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictogrammes

Corrosion
GHS05

Mention d'avertissement

Warning

Mentions de danger

H290

Conseils de prudence

P234 - P390

Classification des risques

Met. Corr. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Certificats d'analyse (COA)

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Articles

dECM hydrogels 3D culture

Comparison of decellularized extracellular matrix (dECM) hydrogels to Matrigel® matrices for predictive 3D cell culture models

Hydrogels for 3D Cell Culture

Hydrogela are the most widely used systems for 3D cell culture. Learn more about this technology (what are hydrogels? How to chose?)

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

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