ABS521

Anti-RSK4 Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Q9UK32, KS6A6_HUMAN, RPS6KA6, RSK4, Q9UK32, B2R854, Q6FHX2, Q8WX28, Q9H4S6, Ribosomal protein S6 kinase alpha-6, p90RSK6
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: rat
• Réactivité de l'espèce (prédite par homologie): human (based on 100% sequence homology), bovine (based on 100% sequence homology)
• Technique(s): immunoprecipitation (IP): suitable; western blot: suitable
• Numéro d'accès NCBI: NP_055311
• Numéro d'accès UniProt: Q9UK32
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... RPS6KA6(27330)

Description

Description générale

RSK1, RSK2, RSK3, and RSK4 (ribosomal protein S6 kinase, 90 kDa, polypeptide 1,2,3, and 4; S6K-alpha 1,2,3, and 4) are Ser/Thr kinases which are activated by MAP Kinases. Ribosomal S6-kinase 4 (RSK4) is thought to be mapped in the critical region that is commonly deleted in X-linked deafness type 3, mental retardation, and choroideremia. It may be involved in normal neuronal development. RSK4 is also thought to play a role in non-growth factor signaling and may also be important in tumor suppression.

Immunogène

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of Human RSK4.

Application

Immunoprecipitation analysis: 10 ug of Cat. No. ABS521, Anti-RSK4 was used to immunoprecipitate RSK4 in 0.5 mg PC12 or EGF treated PC12 cell lysate
Immunoprecipitation analysis: 5 ug of Cat. No. ABS521, Anti-RSK4 was used to immunoprecipitate RSK4 in 0.665mg of PC12 cell lysate. Uncharacterized bands may be detected at high antibody concentration or longer exposures

Research Category
Signaling

Research Sub Category
Kinases & Phosphatases

General Post-translation Modification

This Anti-RSK4 Antibody is validated for use in Western Blotting and Immunoprecipitation for the detection of RSK4.

Qualité

Evaluated by Western Blotting in rat PC12 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected RSK4 in 10 µg of rat PC12 cell lysate.

Description de la cible

~83 kDa observed. Uncharacterized band(s) may appear in some lysates.

Liaison

Replaces: 04-1132

Forme physique

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Autres remarques

Concentration: Please refer to lot specific datasheet.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable