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ABC350

Sigma-Aldrich

Anti-CIDE-A Antibody

from rabbit, purified by affinity chromatography

Synonyme(s) :

Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

mouse

Technique(s)

immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

mouse ... Cidea(12683)

Description générale

Cell death activator CIDE-A (CIDE-A) binds to lipid droplets and regulates their enlargement which restricts lipolysis and favoring storage. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. CIDE-A is highly expressed in brown adipose tissue and, at lower levels, in white adipose tissue.

Spécificité

This antibody recognizes the C-terminus of CIDE-A.

Immunogène

Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of mouse CIDE-A.

Application

Detect CIDE-A using this rabbit polyclonal antibody, Anti-CIDE-A Antibody validated for use in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected CIDE-A in mouse heart tissue.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected CIDE-A in mouse heart tissue.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

Qualité

Evaluated by Western Blotting in mouse heart tissue lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected CIDE-A in 15 µg of mouse heart tissue lysate.

Description de la cible

~25 kDa observed

Forme physique

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Mouse heart tissue lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Achintya Patel et al.
Journal of cellular and molecular medicine, 26(15), 4183-4194 (2022-07-09)
Excessive dietary intake of fat results in its storage in white adipose tissue (WAT). Energy expenditure through lipid oxidation occurs in brown adipose tissue (BAT). Certain WAT depots can undergo a change termed beiging where markers that BAT express are

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