AB15794
Anti-Dexras1 Antibody
Chemicon®, from rabbit
Synonyme(s) :
Activator of G-Protein Signaling 1, AGS1
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
affinity isolated antibody
Type de produit anticorps
primary antibodies
Clone
polyclonal
Produit purifié par
affinity chromatography
Espèces réactives
mouse
Réactivité de l'espèce (prédite par homologie)
rat (100% immunogen homology), human (100% immunogen homology)
Fabricant/nom de marque
Chemicon®
Technique(s)
western blot: suitable
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... RASD1(51655)
Description générale
Dexras1 is a member of the superfamily of RAS-g-proteins and directly binds to Gialpha heterotrimeric G-proteins where it appears to promote guanine nucleotide exchange on Gialpha. Dexras1 is implicated in NMDA receptor signaling through nitric oxide synthase.
Spécificité
Dexras1 (Activator of G-Protein Signaling 1, AGS1). By Western blot the antibody recognizes a band at ~33 kDa on mouse brain extract. The antibody has also been used to detect Dexras1 in brown adipocyte lysate.
Other species have not been tested
Immunogène
Synthetic peptide.
Application
Research Category
Neuroscience
Neuroscience
Research Sub Category
Signaling Neuroscience
Signaling Neuroscience
This Anti-Dexras1 Antibody is validated for use in WB for the detection of Dexras1.
Western blot: 1:1,000 on mouse brain extract.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Forme physique
ImmunoAffinity Purified
Liquid in PBS. Contains no preservative
Stockage et stabilité
6 months at -70°C from date of shipment
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Marek Lenarczyk et al.
Journal of molecular histology, 46(2), 123-136 (2014-12-24)
Activators of G-protein Signaling (AGS) are a family of accessory proteins that were discovered as modulators of heterotrimeric G-protein subunits. The primary aim of the present study was to localize Group I and II AGS proteins and determine the renal
Yu Zhang et al.
Aging cell, 17(3), e12754-e12754 (2018-03-27)
In neurons, increased protein-protein interactions between neuronal nitric oxide synthase (nNOS) and its carboxy-terminal PDZ ligand (CAPON) contribute to excitotoxicity and abnormal dendritic spine development, both of which are involved in the development of Alzheimer's disease. In models of Alzheimer's
Sudhir G Tattikota et al.
Molecular & cellular proteomics : MCP, 12(5), 1214-1225 (2013-01-30)
Argonaute2 (Ago2) is an established component of the microRNA-induced silencing complex. Similar to miR-375 loss-of-function studies, inhibition of Ago2 in the pancreatic β-cell resulted in enhanced insulin release underlining the relationship between these two genes. Moreover, as the most abundant
Li-Juan Zhu et al.
Journal of neurochemistry, 146(5), 598-612 (2018-06-03)
Anxiety disorders are associated with a high social burden worldwide. Recently, increasing evidence suggests that nuclear factor kappa B (NF-κB) has significant implications for psychiatric diseases, including anxiety and depressive disorders. However, the molecular mechanisms underlying the role of NF-κB
Sudhir G Tattikota et al.
Cell metabolism, 19(1), 122-134 (2013-12-24)
Pancreatic β cells adapt to compensate for increased metabolic demand during insulin resistance. Although the microRNA pathway has an essential role in β cell proliferation, the extent of its contribution is unclear. Here, we report that miR-184 is silenced in
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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