5.05412

1,1-Dimethyl-4-phenylpiperazinium iodide

• Synonyme(s) : 1,1-Dimethyl-4-phenylpiperazinium iodide, 1,1-dimethyl-4-phenylpiperazinium, Nicotinic Acetylcholine Receptor (nAChR) Agonist, DMPP, (α3)2(β4)3 Nicotinic Acetylcholine Receptor (nAChR) Agonist, DMPP, Ganglionic Nicotinic Acetylcholine Receptor (nAChR) Agonist, DMPP
• Formule empirique (notation de Hill): C₁₂H₁₉IN₂
• Numéro CAS: 54-77-3
• Poids moléculaire : 318.20
• Numéro MDL: MFCD00011976
• Code UNSPSC : 12352200

Propriétés

• Pureté: ≥98% (titration)
• Niveau de qualité: 100
• Forme: powder
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; protect from light
• Couleur: white
• Solubilité: 50% acetic acid: 50 mg/mL
• Température de stockage: 2-8°C
• InChI: 1S/C12H19N2.HI/c1-14(2)10-8-13(9-11-14)12-6-4-3-5-7-12;/h3-7H,8-11H2,1-2H3;1H/q+1;/p-1
• Clé InChI: XFZJGFIKQCCLGK-UHFFFAOYSA-M

Description

Description générale

An agonist selective for ganglionic subtype of acetylcholine receptors (nAChR) and acts as a ganglionic stimulant. At higher concentrations also inhibits the uptake of NE and 5-HT.

Actions biochimiques/physiologiques

Primary Target
nAChR

Avertissement

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Autres remarques

Chen, R., et al., 1951. J. Pharmacol. Exp. Ther. 103.
Vizi, S., 1999. Brain Res. Brain Res. Rev.30, 219.
Prado. W., et al. 2004. Brain Res.1018, 272.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable