454565

Methyl Arachidonyl Fluorophosphonate - Calbiochem

• Synonyme(s) : Methyl Arachidonyl Fluorophosphonate - Calbiochem, MAFP, cPLA2α Inhibitor III
• Formule empirique (notation de Hill): C₂₁H₃₆FO₂P
• Poids moléculaire : 370.48
• Code UNSPSC : 12352200

Propriétés

• Pureté: ≥98% (TLC)
• Niveau de qualité: 100
• Forme: liquid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Conditions d'expédition: wet ice
• Température de stockage: −70°C

Description

Description générale

This product has been discontinued.

A selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A₂ (PLA₂) but not of secretory PLA₂.

A selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A₂ (PLA₂) but not secretory PLA₂.

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2)

Product does not compete with ATP.

Reversible: no

Avertissement

Toxicity: Standard Handling (A)

Forme physique

In methyl acetate.

Reconstitution

Prior to use, evaporate the methyl acetate and resuspend in high quality chloroform. Aliquot and immediately evaporate the chloroform. Store aliquots at -70°C. Reconstitute in DMSO just prior to use.

Autres remarques

Balsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
Lio, Y.C., et al. 1996. Biochim. Biophys. Acta1302, 55.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany