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235752

Sigma-Aldrich

Anti-C-Reactive Protein Rabbit pAb

liquid, Calbiochem®

Synonyme(s) :

Anti-CRP

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

liquid

Contient

≤0.1% sodium azide as preservative

Espèces réactives

human

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze
avoid repeated freeze/thaw cycles

Isotype

IgG

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... CRP(1401)

Description générale

Rabbit polyclonal antibody purified by DEAE anion exchange chromatography. Recognizes C-reactive protein.
Recognizes C-reactive protein. Does not exhibit cross-reactivity against normal human serum.

Immunogène

purified, human CRP

Application

ELISA (see application references)

Immunoblotting (0.1 µg/ml,see application references)

Immunoprecipitation (see comments)

Radioimmunoassay (see comments)

Conditionnement

Please refer to vial label for lot-specific concentration.

Avertissement

Toxicity: Standard Handling (A)

Forme physique

In 100 mM NaCl, 15 mM phosphate buffer, pH 7.2-7.4.

Autres remarques

Exhibits a single precipitin line against CRP control serum. Does not exhibit cross-reactivity against normal human serum. The optimal dilution for RIA and immunoprecipitation should be determined for each sample type. Antibody should be titrated for optimal results in individual systems.
Ridker, P.M., et al. 1997. N. Engl. J. Med.336, 973.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Donald N Ngwa et al.
Frontiers in immunology, 11, 586669-586669 (2020-10-30)
C-reactive protein (CRP) binds to several species of bacterial pathogens including Streptococcus pneumoniae. Experiments in mice have revealed that one of the functions of CRP is to protect against pneumococcal infection by binding to pneumococci and activating the complement system.
Maurice Swinkels et al.
Scientific reports, 8(1), 1643-1643 (2018-01-28)
Retinal inflammation plays a key role in the progression of age-related macular degeneration (AMD), a condition that leads to loss of central vision. The deposition of the acute phase pentraxin C-reactive protein (CRP) in the macula activates the complement system
Anika Alberts et al.
Frontiers in immunology, 11, 596103-596103 (2020-12-29)
Endogenous and exogenous crystalline structures are involved in various pathologies and diseases in humans by inducing sterile inflammation, mechanical stress, or obstruction of excretory organs. The best studied of these diseases is gout, in which crystallization of uric acid in
Asmita Pathak et al.
Frontiers in immunology, 11, 1780-1780 (2020-08-28)
The aim of this study was to test the hypothesis that C-reactive protein (CRP) protects against the development of atherosclerosis and that a conformational alteration of wild-type CRP is necessary for CRP to do so. Atherosclerosis is an inflammatory cardiovascular
Anika Alberts et al.
Scientific reports, 10(1), 6391-6391 (2020-04-15)
Gout is caused by crystallization of uric acid in the form of monosodium urate (MSU) crystals, which induce a sterile inflammatory response that is hardly distinguishable from microbe-induced inflammatory responses. It is unclear, if MSU crystals (like microbes) are recognized
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